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Oxalosuccinic acid

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Oxalosuccinic acid
Names
IUPAC name 1-Oxopropane-1,2,3-tricarboxylic acid
Identifiers
CAS Number
3D model (JSmol)
ECHA InfoCard 100.230.021 Edit this at Wikidata
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • C(C(C(=O)C(=O)O)C(=O)O)C(=O)O
Properties
Chemical formula C6H6O7
Molar mass 190.108
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Oxalosuccinic acid is a substrate of the citric acid cycle. It is acted upon by isocitrate dehydrogenase. Salts and esters of oxalosuccinic acid are known as oxalosuccinates.

Citric acid cycle metabolic pathway

Acetyl-CoA

+ H2O

Oxaloacetate

Leftward reaction arrow with minor product(s) to bottom left and minor substrate(s) from bottom rightNADH +H NAD

Malate

Leftward reaction arrow with minor substrate(s) from bottom right  H2O

Fumarate

Leftward reaction arrow with minor product(s) to bottom left and minor substrate(s) from bottom rightFADH2 FAD

Succinate

Leftward reaction arrow with minor product(s) to bottom left and minor substrate(s) from bottom rightCoA + ATP (GTP) Pi + ADP (GDP)

Succinyl-CoA

NADH + H + CO2
CoA NAD

Citrate

  H2O Rightward reaction arrow with minor product(s) to top right

cis-Aconitate

H2O   Rightward reaction arrow with minor substrate(s) from top left

Isocitrate

NAD(P) NAD(P)H +  H Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right

Oxalosuccinate

  CO2 Rightward reaction arrow with minor product(s) to top right

2-oxoglutarate


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