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TCPy

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TCPy
Names
IUPAC name 3,5,6-Trichloro-1H-pyridin-2-one
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.026.733 Edit this at Wikidata
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)Key: WCYYAQFQZQEUEN-UHFFFAOYSA-N
  • InChI=1/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)Key: WCYYAQFQZQEUEN-UHFFFAOYAM
SMILES
  • O=C1C(Cl)=CC(Cl)=C(Cl)N1
Properties
Chemical formula C5H2Cl3NO
Molar mass 198.43 g·mol
Density 1.67g/cm
Melting point 172-174°C
Boiling point 254.8°C @760mmHg
Hazards
Flash point 107.9°C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

TCPy or 3,5,6-trichloro-2-pyridinol is a metabolite of chlorpyrifos and chlorpyrifos-methyl, both organophosphate insecticides. A study in Massachusetts reported a correlation between exposure to TCPy and lower testosterone levels in men. According to this source, exposure is "widespread" and of "potential public health importance".

References

  1. Meeker, John D.; Ryan, Louise; Barr, Dana B.; Hauser, Russ (2006). "Exposure to Nonpersistent Insecticides and Male Reproductive Hormones". Epidemiology. 17 (1): 61–68. doi:10.1097/01.ede.0000190602.14691.70. PMID 16357596.{{cite journal}}: CS1 maint: multiple names: authors list (link)
Pest control: Insecticides
Carbamates
Inorganic compounds
Insect growth regulators
Neonicotinoids
Organochlorides
Organophosphorus
Pyrethroids
Diamides
Other chemicals
Metabolites
Biopesticides
Categories: