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VUAA1

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VUAA1
Names
IUPAC name 2-(4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-ylthio)-N-(4-ethylphenyl)acetamide
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C19H21N5OS/c1-3-14-7-9-16(10-8-14)21-17(25)13-26-19-23-22-18(24(19)4-2)15-6-5-11-20-12-15/h5-12H,3-4,13H2,1-2H3,(H,21,25)Key: UWCCKVJVOHTHAF-UHFFFAOYSA-N
SMILES
  • CCN1C(C2=CN=CC=C2)=NN=C1SCC(NC3=CC=C(CC)C=C3)=O
Properties
Chemical formula C19H21N5OS
Molar mass 367.468
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

VUAA1 is a chemical compound that works by over activating an insect's olfactory senses causing a repellent effect. It was recently discovered at Vanderbilt University.

VUAA1 is first-in-class agonist believed to work by overloading an insect's odorant receptors. This new class of chemicals is said to be 1000 times stronger than DEET and may lead to, "a powerful new family of compounds that can be used to disrupt the destructive behaviors of nuisance insects, agricultural pests, and disease vectors alike."

References

  1. Jones PL, Pask GM, Rinker DC, Zwiebel LJ. Functional agonism of insect odorant receptor ion channels. Proceedings of the National Academy of Sciences USA. 2011 May 9. PMID 21555561
  2. "New type of insect repellent may be thousands of times stronger than DEET" (Press release). physorg.com. May 9, 2011.
  3. "Functional agonism of insect odorant receptor ion channel" (Press release). April 4, 2011.

External links

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