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Drostanolone propionate

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Revision as of 02:09, 1 September 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (report errors or bugs))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Dromostanolone
Clinical data
Pregnancy
category
  • X
Routes of
administration
Intramuscular injection or transdermal cream
ATC code
Legal status
Legal status
Pharmacokinetic data
BioavailabilityOral 0-2%, Intramuscular 100%
Protein bindinghighly
Metabolismhepatic
Elimination half-life2-3 Days
Excretionrenal
Identifiers
IUPAC name
  • (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopentaphenanthren-3-one
CAS Number
PubChem CID
DrugBank
ChemSpider
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.007.550 Edit this at Wikidata
Chemical and physical data
FormulaC23H36O3
Molar mass360.53 g/mol g·mol
3D model (JSmol)
SMILES
  • CCC(=O)O1CC21(CC32CC43(C(C(=O)C4)C)C)C
InChI
  • InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1
  • Key:NOTIQUSPUUHHEH-UXOVVSIBSA-N
  (verify)

Drostanolone propionate (trade name Masteron) is an anabolic/androgenic steroid which is the propionate ester of drostanolone. It is known to be highly androgenic and mildly anabolic. It is incapable of aromatization and has similar properties to dihydrotestosterone. It has been successfully used as a breast cancer drug, but because of the high risk of virilization, safer options are prescribed.

Use in sports

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Drostanolone propionate is used primarily by athletes who need to retain strength while losing mass. It is beneficial to runners and athletes who must remain in a certain weight class.

It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug. Individuals interested in using the drostanolone propionate are those that are looking to add muscle hardness and density to their physiques, nearly always for the purpose of bodybuilding competitions.

Drostanolone propionate can increase muscle hardness and density, giving an individual a more complete appearance when competing on stage. However, an already rather low body-fat level is needed for it to take full effect. Drostanolone propionate can promote increased strength while keeping body fat the same or even lowering it, something can help to prevent muscle loss while dieting. This can also allow strength athletes or those athletes in sports which have weight classes to increase performance without the risk of being raised into a higher weight class or add mass that may hinder performance.

References

  1. Chowdhury MS, Banks AJ, Bond WH, Jones WG, Ward HW (1976). "A comparison of drostanolone propionate (Masteril) and nandrolone decanoate (Deca-durabolin) in the treatment of breast carcinoma". Clin Oncol. 2 (3): 203–6. PMID 103698.{{cite journal}}: CS1 maint: multiple names: authors list (link)


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