Phenindione - Misplaced Pages

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Revision as of 09:03, 22 October 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (changes to verified fields - updated 'CAS_number_Ref') per Chem/Drugbox validation (report errors or bugs))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound

Phenindione
Clinical data

AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: D Passes into breast milk
Routes of administration	Oral
ATC code	B01AA02 (WHO)
Pharmacokinetic data
Protein binding	88%
Elimination half-life	5 to 10 hours
Identifiers
IUPAC name 2-phenyl-1H-indene-1,3(2H)-dione
CAS Number	83-12-5
PubChem CID	4760
DrugBank	APRD00166
ChemSpider	4596
UNII	5M7Y6274ZE
KEGG	D08354
ChEBI	CHEBI:8066
ChEMBL	ChEMBL711
CompTox Dashboard (EPA)	DTXSID5023453
ECHA InfoCard	100.001.323
Chemical and physical data
Formula	C₁₅H₁₀O₂
Molar mass	222.239 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES O=C2c1ccccc1C(=O)C2c3ccccc3
InChI InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H Key:NFBAXHOPROOJAW-UHFFFAOYSA-N
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Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Hypersensitivity has been observed.

References

Naisbitt DJ; Farrell J; Chamberlain PJ; et al. (2005). "Characterization of the T-cell response in a patient with phenindione hypersensitivity". J. Pharmacol. Exp. Ther. 313 (3): 1058–65. doi:10.1124/jpet.105.083758. PMID 15743920. {{cite journal}}: Unknown parameter |author-separator= ignored (help); Unknown parameter |month= ignored (help)

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