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Cefixime

Clinical data
Trade names	Suprax
AHFS/Drugs.com	Monograph
MedlinePlus	a690007
Pregnancy category	B
Routes of administration	Oral
ATC code	J01DD08 (WHO)
Pharmacokinetic data
Bioavailability	40% to 50%
Protein binding	Approximately 60%
Elimination half-life	Variable Average 3 to 4 hours
Excretion	Renal and biliary
Identifiers
IUPAC name (6R,7R)-7-{amino}-3-ethenyl-8-oxo-5-thia- 1-azabicyclooct-2-ene-2-carboxylic acid
CAS Number	79350-37-1
PubChem CID	5362065
DrugBank	DB00671
ChemSpider	4514923
UNII	97I1C92E55
KEGG	D00258
ChEBI	CHEBI:472657
ChEMBL	ChEMBL1541
CompTox Dashboard (EPA)	DTXSID7022754
ECHA InfoCard	100.119.331
Chemical and physical data
Formula	C16H15N5O7S2
Molar mass	453.452 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(/C=C)CS12NC(=O)C(=N\OCC(=O)O)/c3nc(sc3)N)C(=O)O
InChI InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1 Key:OKBVVJOGVLARMR-QSWIMTSFSA-N
(verify)

Cefixime is an oral third generation cephalosporin antibiotic. Cefixime is a cephalosporin antibiotic used to treat infections caused by bacteria such as pneumonia; bronchitis; gonorrhea; and ear, lung, throat, and urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections.

It was sold under the trade name Suprax in the USA until 2003 when it was taken off the market by drug manufacturer Wyeth after its patent expired. The oral suspension form of "Suprax" was re-launched by Lupin in the USA.

Cefixime API is manufactured by many pharmaceutical companies the world over. The major manufacturers are based in India.

References

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a690007.html

• Cephalosporin antibiotics
• Thiazoles