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Diclofenamide

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This is an old revision of this page, as edited by Beetstra (talk | contribs) at 14:52, 15 November 2011 (Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'DrugBank').). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 14:52, 15 November 2011 by Beetstra (talk | contribs) (Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'DrugBank').)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Diclofenamide
Clinical data
AHFS/Drugs.comInternational Drug Names
MedlinePlusa601233
ATC code
Pharmacokinetic data
Protein binding55%
Identifiers
IUPAC name
  • 4,5-dichlorobenzene-1,3-disulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.004.037 Edit this at Wikidata
Chemical and physical data
FormulaC6H6Cl2N2O4S2
Molar mass305.16 g/mol g·mol
3D model (JSmol)
SMILES
  • Clc1c(cc(cc1Cl)S(=O)(=O)N)S(=O)(=O)N
InChI
  • InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
  • Key:GJQPMPFPNINLKP-UHFFFAOYSA-N
  (verify)

Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.

References

  • Tawil R, McDermott M, Brown R, Shapiro B, Ptacek L, McManis P, Dalakas M, Spector S, Mendell J, Hahn A, Griggs R (2000). "Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis". Ann Neurol. 47 (1): 46–53. doi:10.1002/1531-8249(200001)47:1<46::AID-ANA9>3.0.CO;2-H. PMID 10632100.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Okada S, Izumi W, Murai M, Komatsu H, Ishimitsu S (1991). "". Eisei Shikenjo Hokoku. 109 (109): 148–50. PMID 1364383.{{cite journal}}: CS1 maint: multiple names: authors list (link)
Drugs used for glaucoma preparations and miosis (S01E)
Sympathomimetics
Parasympathomimetics
muscarinic
muscarinic/nicotinic
acetylcholinesterase inhibitors
Carbonic anhydrase inhibitors/
(sulfonamides)
Beta blocking agents
Prostaglandin analogues (F2α)
Other agents
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