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1,3-Difluoro-2-propanol

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This is an old revision of this page, as edited by Chris the speller (talk | contribs) at 05:55, 24 December 2011 (Typo fixing, use degree symbol, not masculine ordinal indicator or superscripted "o", replaced: 25 <sup>o</sup>C → 25 °C (3), 54-55 ° → 54–55 ° using AWB (7852)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 05:55, 24 December 2011 by Chris the speller (talk | contribs) (Typo fixing, use degree symbol, not masculine ordinal indicator or superscripted "o", replaced: 25 <sup>o</sup>C → 25 °C (3), 54-55 ° → 54–55 ° using AWB (7852))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
1,3-Difluoro-2-propanol
Names
IUPAC name 1,3-Difluoro-2-propanol
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.561 Edit this at Wikidata
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2Key: PVDLUGWWIOGCNH-UHFFFAOYSA-N
  • InChI=1/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2Key: PVDLUGWWIOGCNH-UHFFFAOYAJ
SMILES
  • OC(CF)CF
  • FCC(O)CF
Properties
Chemical formula C3H6F2O
Molar mass 96.077 g·mol
Density 1.24 g/cm (at 25 °C)
Boiling point 54–55 °C
Hazards
Flash point 42 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor which was widely used in the former USSR.

References

  1. http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=de&N4=176923%7CALDRICH&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&F=SPEC
  2. Buklan AI, Kravets AF (1986). "". Sud. Med. Ekspert. (in Russian). 29 (1): 55–6. PMID 3961873.
  3. Feldwick MG, Noakes PS, Prause U, Mead RJ, Kostyniak PJ (1998). "The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote". J. Biochem. Mol. Toxicol. 12 (1): 41–52. doi:10.1002/(SICI)1099-0461(1998)12:1<41::AID-JBT6>3.0.CO;2-P. PMID 9414486.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. Menon KI, Feldwick MG, Noakes PS, Mead RJ (2001). "The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (-)-erythro-fluorocitrate". J. Biochem. Mol. Toxicol. 15 (1): 47–54. doi:10.1002/1099-0461(2001)15:1<47::AID-JBT6>3.0.CO;2-E. PMID 11170315.{{cite journal}}: CS1 maint: multiple names: authors list (link)
Pest control: Rodenticides
Anticoagulants /
Vitamin K antagonists
Coumarins /
4-Hydroxycoumarins
1st generation
2nd generation (Superwarfarins)
1,3-Indandiones
Convulsants
Calciferols
Inorganic compounds
Organochlorine
Organophosphorus
Carbamates
Others


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