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5-Benzyloxytryptamine

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Revision as of 18:45, 25 December 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (no changed fields - added verified revid - updated 'DrugBank_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'CAS_number_Ref') per Chem/Drugbox validation (report [[Misplaced Pages talk:WikiProject_Pharmac...)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
5-Benzyloxytryptamine
Identifiers
IUPAC name
  • 2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.040.007 Edit this at Wikidata
Chemical and physical data
FormulaC17H18N2O
Molar mass266.34 g/mol g·mol
3D model (JSmol)
SMILES
  • NCCC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C21
InChI
  • InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
  • Key:WKPDXBXNJWWWGQ-UHFFFAOYSA-N
  (verify)

5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.

See also

References

  1. Lyon RA, Titeler M, Seggel MR, Glennon RA (1988). "Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens". European Journal of Pharmacology. 145 (3): 291–7. doi:10.1016/0014-2999(88)90432-3. PMID 3350047. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. Peroutka SJ, McCarthy BG, Guan XM (1991). "5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent". Life Sciences. 49 (6): 409–18. doi:10.1016/0024-3205(91)90582-V. PMID 1650872.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. Cohen ML, Schenck K, Nelson D, Robertson DW (1992). "Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins". European Journal of Pharmacology. 211 (1): 43–6. doi:10.1016/0014-2999(92)90260-B. PMID 1319907. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  4. Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). "Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells". Neuropharmacology. 36 (4–5): 713–20. doi:10.1016/S0028-3908(97)00019-1. PMID 9225298.{{cite journal}}: CS1 maint: multiple names: authors list (link)


Serotonin receptor modulators
5-HT1
5-HT1A
5-HT1B
5-HT1D
5-HT1E
5-HT1F
5-HT2
5-HT2A
5-HT2B
5-HT2C
5-HT37
5-HT3
5-HT4
5-HT5A
5-HT6
5-HT7
Tryptamines
Tryptamines
N-Acetyltryptamines
α-Alkyltryptamines
Triptans
Cyclized tryptamines
Isotryptamines
Related compounds


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