Misplaced Pages

Phosphoribosyl pyrophosphate

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.

This is an old revision of this page, as edited by CheMoBot (talk | contribs) at 18:56, 6 January 2012 (Updating {{chembox}} (no changed fields - updated 'UNII_Ref', 'ChEMBL_Ref', 'KEGG_Ref', 'CASNo_Ref') per Chem/Drugbox validation (report errors or bugs)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 18:56, 6 January 2012 by CheMoBot (talk | contribs) (Updating {{chembox}} (no changed fields - updated 'UNII_Ref', 'ChEMBL_Ref', 'KEGG_Ref', 'CASNo_Ref') per Chem/Drugbox validation (report errors or bugs))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.
Find sources: "Phosphoribosyl pyrophosphate" – news · newspapers · books · scholar · JSTOR (December 2009) (Learn how and when to remove this message)
Phosphoribosyl pyrophosphate
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
MeSH Phosphoribosyl+pyrophosphate
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C5H13O14P3/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13)/t2-,3-,4-,5-/m1/s1Key: PQGCEDQWHSBAJP-TXICZTDVSA-N
  • InChI=1/C5H13O14P3/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13)/t2-,3-,4-,5-/m1/s1Key: PQGCEDQWHSBAJP-TXICZTDVBW
SMILES
  • O=P(O1O((O)1O)COP(=O)(O)O)(O)OP(=O)(O)O
Properties
Chemical formula C5H13O14P3
Molar mass 390.07 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate.

It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase.

It plays a role in transferring phospho-ribose groups in several reactions:

Enzyme Reactant Product
adenine phosphoribosyltransferase adenine AMP
hypoxanthine-guanine phosphoribosyltransferase guanine GMP
hypoxanthine-guanine phosphoribosyltransferase hypoxanthine IMP
orotate phosphoribosyltransferase orotate OMP
uracil phosphoribosyltransferase uracil UMP

In de novo generation of purines, the enzyme amidophosphoribosyltransferase acts upon PRPP to create phosphoribosylamine.

See also

Nucleotide metabolic intermediates
purine
metabolism
anabolism
R5P→IMP:
IMP→AMP:Adenylosuccinate
IMP→GMP:Xanthosine monophosphate
catabolism
pyrimidine
metabolism
anabolism
catabolism
uracil:
thymine:


Stub icon

This biochemistry article is a stub. You can help Misplaced Pages by expanding it.

Categories: