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Talk:Replisome

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This is an old revision of this page, as edited by Thermodynamic (talk | contribs) at 05:03, 24 April 2012 (Replisome Pro/Euk). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 05:03, 24 April 2012 by Thermodynamic (talk | contribs) (Replisome Pro/Euk)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)

Template:Wikiproject MCB Template:WikiProject Genetics A table listing the enzymes and their tasks should be added. An image would also be helpful. --Artman40 12:29, 31 December 2006 (UTC)

More information for replisome

http://research.chem.psu.edu/sjbgroup/T4Replisome/T4mainpage.html http://www.wehi.edu.au/education/wehi-tv/dna/replication.html These links should help to organize the article. --Artman40 15:41, 10 January 2007 (UTC)

Replisome Pro/Euk

There are some significant differences in replisome factors between prokaryotes and eukaryotes. What's the best way to make sure these differences are made clear?

This article is missing lots of major pieces:

  • In addition to preventing the formation of hairpins, the combination of SSB/RPA + single strand serves as a better substrate for the polymerisation reaction that takes place inside DNA polymerase III.
  • There is almost no discussion about clamp loader/clamp or pre-initiation / initiation complex.
  • There is almost no discussion about how error correction works in DNA polymerase III.
  • There is almost no discussion about processivity.

Thermodynamic (talk) 04:44, 24 April 2012 (UTC)

Is anyone interested in coming up with a realistic table of contents? I can contribute significant portions of the writing for the article, but I'd really like community involvement for the TOC. Thermodynamic (talk) 05:03, 24 April 2012 (UTC)