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Chemical evolution may refer to:

• Stellar nucleosynthesis, the creation of chemical elements by stellar thermonuclear fusion or supernovae
• Abiogenesis, the transition from nonliving elements to living systems
• Evolution of metal ions in biological systems, incorporation of metallic ions into living organisms and how it has changed over time
• Molecular evolution, evolution at the scale of molecules
• Gas evolution reaction, the process of a gas bubbling out from a solution
• Oxygen evolution, the process of generating molecular oxygen through chemical reaction
• Astrochemistry, the study of the abundance and reactions of molecules in the Universe, and their interaction with radiation
• Cosmochemistry, the study of the chemical compositions in the universe and the processes that led to them

• Disambiguation pages