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DDM may refer to:

• Derrick Drilling Machine, or Top drive
• Deutsches Dampflokomotiv-Museum, the German Steam Locomotive Museum
• Dharma Drum Mountain, a Buddhist educational foundation
• Didymoteicho, a Greek town
• Difference in the Depth of Modulation, an amplitude modulation method used in the Instrument Landing System
• Differential dynamic microscopy, an optical technique
• Direct Digital Manufacturing
• Dividend Discount Model, a valuation method for shares based on dividends
• Doctor of Dental Medicine, an academic degree for dentistry
• Domain decomposition methods
• Drift Diffusion Model, a method used in psychological choice testing
• Dubbeldeks Materieel, a class of trains in the Netherlands
• Dungeon Dice Monsters, a board game
• Dungeons & Dragons Miniatures Game, collectible tactical skirmish game
• Dyson Digital Motor, a two-pole switched reluctance motor
• East German mark, a former currency (ISO code was DDM)
• Maltosides (n-Dodecyl β-D-Maltopyranoside), a detergent used when purifying membrane proteins

Information technology

• Data Diffusion Machine, a virtual shared memory computer architecture from the 1990s
• Database Deployment Manager, an open source application for database modelling
• Digital diagnostics monitoring function in SFP transceivers
• Distributed Data Management Architecture, an open, published architecture for creating, managing and accessing data on a remote computer.
• Dynamic Data Masking, a form of data masking
• Dynamic Device Mapping, an advanced technology for USB KVM switches

• Disambiguation pages