| Revision as of 16:22, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 445012274 of page 1,3-Diaminopropane for the Chem/Drugbox validation project (updated: ''). |
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{{Chembox |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{chembox |
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| Watchedfields = changed |
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| Watchedfields = changed |
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| verifiedrevid = 443253818 |
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| verifiedrevid = 477205113 |
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|ImageFile=1,3-Diaminopropane.svg |
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| ImageFile = 1,3-Diaminopropane.svg |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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|ImageSize=180px |
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| ImageSize = 160 |
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|IUPACName=Propane-1,3-diamine |
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| ImageName = Skeletal formula of 1,3-diaminopropane |
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|OtherNames=Trimethylenediamine; TMEDA; propandiamine; 1,3-propylenediamine |
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| PIN = Propane-1,3-diamine |
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| OtherNames = {{Unbulleted list|Propandiamine|1,3-Propylenediamine|Trimethylenediamine|3-Aminopropylamine |
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}} |
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|Section1={{Chembox Identifiers |
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|Section1={{Chembox Identifiers |
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| CASNo = 109-76-2 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| ChEBI = 15725 |
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| UNII = CB3ISL56KG |
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| PubChem = 428 |
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| ChemSpiderID = 415 |
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| ChemSpiderID = 415 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| EINECS = 203-702-7 |
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| UNNumber = 2922 |
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| KEGG = C00986 |
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| KEGG = C00986 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| InChI = 1/C3H10N2/c4-2-1-3-5/h1-5H2 |
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| MeSHName = trimethylenediamine |
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| InChIKey = XFNJVJPLKCPIBV-UHFFFAOYAG |
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| ChEBI = 15725 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 174324 |
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| ChEMBL = 174324 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| RTECS = TX6825000 |
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| Beilstein = 605277 |
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| Gmelin = 1298 |
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| 3DMet = B00214 |
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| SMILES = NCCCN |
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| StdInChI = 1S/C3H10N2/c4-2-1-3-5/h1-5H2 |
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| StdInChI = 1S/C3H10N2/c4-2-1-3-5/h1-5H2 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = XFNJVJPLKCPIBV-UHFFFAOYSA-N |
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| StdInChIKey = XFNJVJPLKCPIBV-UHFFFAOYSA-N |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| CASNo=109-76-2 |
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| PubChem=428 |
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| SMILES = NCCCN |
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|Section2={{Chembox Properties |
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|Section2={{Chembox Properties |
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| C = 3 | H = 10 | N = 2 |
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| C=3 | H=10 | N=2 |
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| Appearance= |
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| Appearance = Colourless liquid |
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| Odor = Fishy, ammoniacal |
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| Density=0.880 g/mL |
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| Density = 0.888 g mL<sup>−1</sup> |
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| MeltingPt= |
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| MeltingPtK = 261.15 |
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| BoilingPt= |
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| BoilingPtK = 413.2 |
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| Solubility= |
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| LogP = −1.4 |
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| VaporPressure = <1.1 kPa or 11.5 mm Hg(at 20 °C) |
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| RefractIndex = 1.458 |
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| MagSus = -58.1·10<sup>−6</sup> cm<sup>3</sup>/mol |
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|Section3={{Chembox Hazards |
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|Section3={{Chembox Hazards |
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| GHSPictograms = {{GHS flame}} {{GHS corrosion}} {{GHS skull and crossbones}} |
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| ExternalMSDS = |
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| GHSSignalWord = '''DANGER''' |
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| EUClass = {{Hazchem T}} {{Hazchem C}} |
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| HPhrases = {{H-phrases|226|302|310|314}} |
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| FlashPt= |
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| PPhrases = {{P-phrases|280|302+350|305+351+338|310}} |
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| Autoignition= |
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| NFPA-H = 3 |
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| NFPA-F = 3 |
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| NFPA-R = 0 |
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| FlashPtC = 51 |
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| AutoignitionPtC = 350 |
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| ExploLimits = 2.8–15.2% |
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| LD50 = {{Unbulleted list|177 mg kg<sup>−1</sup> <small>(dermal, rabbit)</small>|700 mg kg<sup>−1</sup> <small>(oral, rat)</small>}} |
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|Section4={{Chembox Related |
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| OtherFunction_label = alkanamines |
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| OtherFunction = {{Unbulleted list|]|]|]|]|]|]|]|]|]|]}} |
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| OtherCompounds = ] |
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'''1,3-Diaminopropane''', also known as {{Not a typo|trimethylenediamine}}, is a simple ] with the formula H<sub>2</sub>N(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub>. A colourless liquid with a fishy odor, it is soluble in water and many polar organic solvents. It is isomeric with ]. Both are building blocks in the synthesis of ]s, such as those used in ], and ]es. It is prepared by the amination of ] followed by ] of the resulting ].<ref name=Ullmann>Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. {{doi|10.1002/14356007.a02_001}}</ref> |
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The potassium salt was used in the ].<ref>{{cite journal | author = C. A. Brown and A. Yamashita | title = Saline hydrides and superbases in organic reactions. IX. Acetylene zipper. Exceptionally facile contrathermodynamic multipositional isomeriazation of alkynes with potassium 3-aminopropylamide | year = 1975 | journal = ] | volume = 97 | issue = 4 | pages = 891–892 | doi = 10.1021/ja00837a034}}</ref> |
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Known uses of 1,3-diaminopropane are in the synthesis of ] and ]. |
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== Safety== |
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1,3-Diaminopropane is toxic on skin exposure with an {{LD50}} of 177 mg kg<sup>−1</sup> (dermal, rabbit) |
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==References== |
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{{Reflist}} |
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{{Ionotropic glutamate receptor modulators}} |
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{{DEFAULTSORT:Diaminopropane, 1,3-}} |
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] |
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] |