| Revision as of 17:13, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 440306455 of page 2-Aminopyridine for the Chem/Drugbox validation project (updated: ''). |
Latest revision as of 22:14, 1 November 2024 edit JWBE (talk | contribs)Extended confirmed users10,126 edits added Category:2-Pyridyl compounds using HotCat |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Chembox |
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{{Chembox |
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| Watchedfields = changed |
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| Watchedfields = changed |
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| verifiedrevid = 410134784 |
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| verifiedrevid = 477212553 |
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| ImageFile = 2-aminopyridine.svg |
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| ImageFile = 2-aminopyridine.svg |
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| ImageSize = 120px |
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| ImageSize = 120px |
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| IUPACName = Pyridin-2-amine |
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| PIN = Pyridin-2-amine |
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| OtherNames = 2-Pyridinamine; 2-Pyridylamine; α-Aminopyridine |
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| OtherNames = 2-Pyridinamine; 2-Pyridylamine; α-Aminopyridine; α-Pyridylamine<ref name=NIOSH/> |
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| Section1 = {{Chembox Identifiers |
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|Section1={{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 10008 |
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| ChemSpiderID = 10008 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 21619 |
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| ChEMBL = 21619 |
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| EC_number = 207-988-4 |
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| RTECS = US1575000 |
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| UNNumber = 2671 |
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| UNII = WSX981HEWU |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7) |
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| StdInChI = 1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7) |
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| SMILES = n1ccccc1N |
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| SMILES = n1ccccc1N |
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}} |
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| Section2 = {{Chembox Properties |
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|Section2={{Chembox Properties |
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| C=5|H=6|N=2 |
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| C=5 | H=6 | N=2 |
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| Appearance = colourless solid |
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| Appearance = colourless solid |
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| Density = |
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| Density = |
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| MeltingPt = 59-60 °C |
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| MeltingPtC = 59 to 60 |
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| MeltingPt_notes = |
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| BoilingPt = 210 °C |
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| Solubility = }} |
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| BoilingPtC = 210 |
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| BoilingPt_notes = |
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| Section3 = {{Chembox Hazards |
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| Solubility = >100%<ref name=NIOSH/> |
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}} |
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|Section3={{Chembox Hazards |
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| MainHazards = |
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| MainHazards = |
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| FlashPtF = 154<ref name=NIOSH/> |
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| FlashPt = |
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| Autoignition = }} |
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| AutoignitionPt = |
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| PEL = TWA 0.5 ppm (2 mg/m<sup>3</sup>)<ref name=NIOSH>{{PGCH|0026}}</ref> |
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| REL = TWA 0.5 ppm (2 mg/m<sup>3</sup>)<ref name=NIOSH/> |
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| IDLH = 5 ppm<ref name=NIOSH/> |
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| LD50 = 200 mg/kg (rat, oral)<br/>50 mg/kg (mouse, oral)<ref>{{IDLH|504290|2-Aminopyridine}}</ref> |
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| GHSPictograms = {{GHS06}}{{GHS07}}{{GHS09}} |
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| GHSSignalWord = Danger |
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| HPhrases = {{H-phrases|301|311|312|315|319|335|411}} |
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| PPhrases = {{P-phrases|261|264|270|271|273|280|301+310|302+352|304+340|305+351+338|312|321|322|330|332+313|337+313|361|362|363|391|403+233|405|501}} |
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'''2-Aminopyridine''' is an ] with the formula H<sub>2</sub>NC<sub>5</sub>H<sub>4</sub>N. It is one of three ]ic aminopyridines. It is a colourless solid that is used in the production of the drugs ], ], ], and ]. It is produced by the reaction of ] with ], the ].<ref name=Ullmann>{{Ullmann|first1=Shinkichi|last1=Shimizu|first2=Nanao|last2=Watanabe|first3=Toshiaki|last3=Kataoka|first4=Takayuki|last4= Shoji|first5=Nobuyuki|last5=Abe|first6=Sinji|last6=Morishita|first7=Hisao|last7=Ichimura|title=Pyridine and Pyridine Derivatives|year=2007|doi=10.1002/14356007.a22_399}}</ref> |
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==Structure== |
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Although ] converts significantly to the pyridone ], the related imine tautomer (HNC<sub>5</sub>H<sub>4</sub>NH) is less important for 2-aminopyridine. |
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==Toxicity== |
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The acute toxicity is indicated by the ] = 200 mg/kg (rat, oral). |
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==References== |
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<references/> |
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==External links== |
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* |
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* |
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{{DEFAULTSORT:Aminopyridine, 2-}} |
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] |
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] |