Revision as of 17:54, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 443807638 of page 3-Mercaptopyruvic_acid for the Chem/Drugbox validation project (updated: 'CASNo'). |
Latest revision as of 18:21, 3 June 2020 edit Fswitzer4 (talk | contribs)Extended confirmed users10,572 editsm Validated CAS and added FDA UNII |
Line 1: |
Line 1: |
|
{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
|
|
{{chembox |
|
{{chembox |
|
|
| Verifiedfields = changed |
⚫ |
| verifiedrevid = 443350114 |
|
|
|
| Watchedfields = changed |
⚫ |
|ImageFile=3-Mercaptopyruvic acid.svg |
|
|
⚫ |
| verifiedrevid = 477219224 |
⚫ |
|ImageSize= |
|
|
⚫ |
| ImageFile=3-Mercaptopyruvic acid.svg |
|
|IUPACName=3-mercapto-2-oxopropanoic acid |
|
|
⚫ |
| ImageSize= |
|
|OtherNames= |
|
|
|
| PIN = 2-Oxo-3-sulfanylpropanoic acid |
|
|
| OtherNames= 3-Mercapto-2-oxopropanoic acid<br />3-MPV<br />3-MP |
|
|Section1={{Chembox Identifiers |
|
|Section1={{Chembox Identifiers |
|
|
| IUPHAR_ligand = 5118 |
|
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
|
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
|
| ChemSpiderID = 96 |
|
| ChemSpiderID = 96 |
|
| KEGG_Ref = {{keggcite|correct|kegg}} |
|
| KEGG_Ref = {{keggcite|correct|kegg}} |
Line 18: |
Line 20: |
|
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
|
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
|
| StdInChIKey = OJOLFAIGOXZBCI-UHFFFAOYSA-N |
|
| StdInChIKey = OJOLFAIGOXZBCI-UHFFFAOYSA-N |
|
|
| CASNo_Ref = {{cascite|correct|CAS}} |
|
| CASNo = <!-- blanked - oldvalue: 2464-23-5 --> |
|
|
|
| CASNo=2464-23-5 |
⚫ |
| PubChem=98 |
|
|
| ChEBI_Ref = {{ebicite|correct|EBI}} |
|
| UNII_Ref = {{fdacite|correct|FDA}} |
|
|
| UNII = 5Z1F5OW4YB |
|
⚫ |
| PubChem=98 |
|
|
| ChEBI_Ref = {{ebicite|correct|EBI}} |
|
| ChEBI = 16208 |
|
| ChEBI = 16208 |
|
| SMILES=C(C(=O)C(=O)O)S |
|
| SMILES=C(C(=O)C(=O)O)S |
|
| MeSHName=3-mercaptopyruvic+acid |
|
| MeSHName=3-mercaptopyruvic+acid |
|
}} |
|
}} |
|
|Section2={{Chembox Properties |
|
|Section2={{Chembox Properties |
|
|
| C=3 | H=4 | O=3 | S=1 |
|
| Formula=C<sub>3</sub>H<sub>4</sub>O<sub>3</sub>S |
|
|
|
| Appearance= |
|
| MolarMass=120.12706 |
|
|
| Appearance= |
|
| Density= |
|
| Density= |
|
| MeltingPt= |
|
| MeltingPt= |
|
| BoilingPt= |
|
| BoilingPt= |
|
| Solubility= |
|
| Solubility= |
|
|
}} |
|
}} |
|
|Section3={{Chembox Hazards |
|
|Section3={{Chembox Hazards |
|
| MainHazards= |
|
| MainHazards= |
|
| FlashPt= |
|
| FlashPt= |
|
|
| AutoignitionPt = |
|
| Autoignition= |
|
|
}} |
|
}} |
|
}} |
|
}} |
|
|
|
|
|
'''3-Mercaptopyruvic acid''' is an intermediate in ]. It has been studied as a potential treatment for ], but its ] is too short for it to be clinically effective.<ref>{{cite journal | pmid = 12871026 | year = 2003 | last1 = Nagahara | first1 = N | last2 = Li | first2 = Q | last3 = Sawada | first3 = N | title = Do antidotes for acute cyanide poisoning act on mercaptopyruvate sulfurtransferase to facilitate detoxification? | volume = 3 | issue = 3 | pages = 198–204 | journal = Current Drug Targets. Immune, Endocrine and Metabolic Disorders | doi=10.2174/1568008033340162}}</ref> Instead, ]s, such as ], are being evaluated to compensate for the short half-life of 3-mercaptopyruvic acid.<ref>{{cite journal | pmid = 20705081 | year = 2010 | last1 = Brenner | first1 = M | last2 = Kim | first2 = JG | last3 = Lee | first3 = J | last4 = Mahon | first4 = SB | last5 = Lemor | first5 = D | last6 = Ahdout | first6 = R | last7 = Boss | first7 = GR | last8 = Blackledge | first8 = W | last9 = Jann | first9 = L | last10 = Nagasawa | first10 = HT | last11 = Patterson | first11 = SE | title = Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity | volume = 248 | issue = 3 | pages = 269–76 | doi = 10.1016/j.taap.2010.08.002 | pmc = 3382974 | journal = Toxicology and Applied Pharmacology}}</ref> |
|
|
|
|
|
==See also== |
|
|
* ] |
|
|
|
|
|
==References== |
|
|
{{reflist}} |
|
|
|
|
|
{{DEFAULTSORT:Mercaptopyruvic acid, 3-}} |
|
|
] |
|
|
] |
|
|
] |
|
|
|
|
|
|
|
|
{{organic-compound-stub}} |