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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Drugbox |
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| verifiedrevid = 443400546 |
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| IUPAC_name = |
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| image = <!--Almagate.svg--> |
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<!--Clinical data--> |
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| tradename = |
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| Drugs.com = {{drugs.com|international|almagate}} |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category = |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = Oral |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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<!--Identifiers--> |
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| CAS_number = 66827-12-1 |
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| ATC_prefix = A02 |
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| ATC_suffix = AD03 |
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| PubChem = 71749 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 64792 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 568Z59H7ZJ |
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| UNII = 568Z59H7ZJ |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| verifiedrevid = 437148482 |
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| KEGG = D02821 |
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| IUPAC_name = |
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| image = <!--Almagate.svg--> |
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<!--Chemical data--> |
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| InChI = 1/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9 |
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| chemical_formula = Al<sub>2</sub>Mg<sub>6</sub>(OH)<sub>14</sub>(CO<sub>3</sub>)<sub>2</sub> · 4 H<sub>2</sub>O |
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| molecular_weight = 314.99 |
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| molecular_weight_comment = g/mol |
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| smiles = .......C()=O.....O.O |
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| smiles = .......C()=O.....O.O |
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| InChIKey = MTEOMEWVDVPTNN-MBBIINEJAH |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9 |
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| StdInChI = 1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = MTEOMEWVDVPTNN-UHFFFAOYSA-E |
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| StdInChIKey = MTEOMEWVDVPTNN-UHFFFAOYSA-E |
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| CAS_number = 66827-12-1 |
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| ATC_prefix = A02 |
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| ATC_suffix = AD03 |
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| PubChem = 71749 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 64792 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D02821 |
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| chemical_formula = Al<sub>2</sub>Mg<sub>6</sub>(OH)<sub>14</sub>(CO<sub>3</sub>)<sub>2</sub> · 4 H<sub>2</sub>O |
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| molecular_weight = 314.99 g/mol |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| ⚫ |
| pregnancy_US = <!-- A / B / C / D / X --> |
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| ⚫ |
| pregnancy_category= |
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| ⚫ |
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = Oral |
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}} |
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}} |
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'''Almagate''' (trade name '''Almax''') is an ]- and ]-containing ]. It was first described in 1984.<ref>{{cite pmid|6548918}}</ref><ref>{{cite pmid|6439224}}</ref> |
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'''Almagate''' (trade name '''Almax''') is an ]- and ]-containing ]. It was first described in 1984.<ref>{{cite journal | vauthors = Moragues J, Beneyto JE, Fábregas JL, Spickett RG | title = Characterization of a new crystalline synthetic gastric antacid, almagate | journal = Arzneimittel-Forschung | volume = 34 | issue = 10A | pages = 1346–9 | year = 1984 | pmid = 6548918 | url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2 | format = Free full text }}</ref><ref>{{cite journal | vauthors = Beneyto JE, Fábregas JL, Moragues J, Spickett RG | title = Evaluation of a new antacid, almagate | journal = Arzneimittel-Forschung | volume = 34 | issue = 10A | pages = 1350–4 | year = 1984 | pmid = 6439224 | url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2 | format = Free full text }}</ref> |
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== Adverse effects == |
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== Adverse effects == |
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Almagate is well tolerated. In a ], the most common ]s were diarrhea and nausea.<ref>{{cite pmid|6548926}}</ref> |
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Almagate is well tolerated. In a ], the most common ]s were diarrhea and nausea.<ref>{{cite journal | vauthors = Suau A, Dominguez Martin A, Ferrando Cucarella J, Juncosa Iglesias L, Muñoz Benitez J, Nieto Calvet M, Pérez Gieb J, Pérez Mota A, Pineda Garcia A, Rodriguez Sanchez E | display-authors = 6 | title = Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A multicentre clinical trial | journal = Arzneimittel-Forschung | volume = 34 | issue = 10A | pages = 1380–3 | year = 1984 | pmid = 6548926 | url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2 | format = Free full text }}</ref> |
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== References == |
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== References == |
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{{gastrointestinal-drug-stub}} |
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{{gastrointestinal-drug-stub}} |
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