| Revision as of 14:50, 17 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 471589900 of page Bis-tris_methane for the Chem/Drugbox validation project (updated: 'ChEBI', 'CASNo'). |
Latest revision as of 22:17, 16 January 2022 edit JJMC89 bot III (talk | contribs)Bots, Administrators3,683,256 editsm Moving Category:Buffers to Category:Buffer solutions per Misplaced Pages:Categories for discussion/Speedy |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{chembox |
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{{chembox |
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| Verifiedfields = changed |
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| verifiedrevid = 391463218 |
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| Watchedfields = changed |
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| Name = Bis-tris methane |
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| verifiedrevid = 477373048 |
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| ImageFile = BisTris.png |
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| ImageFile = BisTris.png |
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<!-- | ImageSize = 200px --> |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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| ImageName = Bis-tris methane |
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| ImageSize = 160 |
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| IUPACName = 2--<br />2-hydroxymethyl-propane-1,3-diol |
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| ImageName = Skeletal formula of bis-tris methane |
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| OtherNames = |
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| PIN = 2--2-(hydroxymethyl)propane-1,3-diol<ref>{{cite web|title=Bistris - Compound Summary|url=https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=81462&loc=ec_rcs#x291|work=PubChem Compound|publisher=National Center for Biotechnology Information|access-date=9 April 2012|location=USA|date=23 June 2005|at=Identification}}</ref> |
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Bis-tris<br /> |
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Bis-(2-hydroxy-ethyl)-<br />amino-tris(hydroxymethyl)-methane<br /> |
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| OtherNames = {{Unbulleted list|Bis-(2-hydroxy-ethyl)-amino-tris(hydroxymethyl)-methane|2--2-(hydroxymethyl)-1,3-propanediol|2,2-Bis(hydroxymethyl)-2,2,2-nitrilotriethanol}} |
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|Section1={{Chembox Identifiers |
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2,2-Bis(hydroxymethyl)-<br />2,2,2-nitrilotriethanol |
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| CASNo = 6976-37-0 |
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| Section1 = {{Chembox Identifiers |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo = <!-- blanked - oldvalue: 6976-37-0 --> |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| SMILES = OCC(CO)(N(CCO)CCO)CO |
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| RTECS = TY2900000 |
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| UNII = Q1XC3631CP |
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| ChEBI = 41250 |
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| PubChem = 81462 |
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| PubChem = 81462 |
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| ChemSpiderID = 73505 |
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| ChemSpiderID = 73505 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| InChI = 1/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
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| EINECS = 230-237-7 |
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| InChIKey = OWMVSZAMULFTJU-UHFFFAOYAD |
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| MeSHName = Bistris |
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| StdInChI = 1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
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| ChEBI = 41250 |
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| StdInChIKey = OWMVSZAMULFTJU-UHFFFAOYSA-N |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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}} |
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| RTECS = |
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| Section2 = {{Chembox Properties |
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| Beilstein = 2205275 |
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| Formula = C<sub>8</sub>H<sub>19</sub>NO<sub>5</sub> |
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| Gmelin = 4519 |
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| MolarMass = 209.2418 g/mol |
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| SMILES = OCCN(CCO)C(CO)(CO)CO |
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| Appearance = white crystalline powder |
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| StdInChI = 1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2 |
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| Density = ? g/l, solid (25°C) |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| Solubility = 67? g/100 ml (20°C) |
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| StdInChIKey = OWMVSZAMULFTJU-UHFFFAOYSA-N |
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| MeltingPt = 102-106°C (375-379K) |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| BoilingPt = (?K) |
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| pKa = 6.46 @25°C |
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}} |
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| Section7 = {{Chembox Hazards |
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| ExternalMSDS = |
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| MainHazards = Irritant. |
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| NFPA-H = 2 |
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| NFPA-F = |
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| NFPA-R = |
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| FlashPt = Non-flammable. |
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| RPhrases = {{R36}}, {{R37}}, {{R38}}. |
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| SPhrases = {{S26}}, {{S36}}. |
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}} |
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}} |
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}} |
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|Section2={{Chembox Properties |
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| C=8 | H=19 | N=1 | O=5 |
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| Appearance = White crystals |
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| Odor = Odourless |
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| MeltingPtC = 102 to 103 |
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| Solubility = 209.2 g L<sup>−1</sup> (at 20 °C) |
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| pKa = 6.46 |
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| pKb = 7.54 |
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| LambdaMax = 280 nm |
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| Absorbance = 0.15 |
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}} |
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|Section3={{Chembox Hazards |
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| GHSPictograms = {{gHS exclamation mark}} |
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| GHSSignalWord = '''WARNING''' |
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| HPhrases = {{h-phrases|315|319|335}} |
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| PPhrases = {{p-phrases|261|305+351+338}} |
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| NFPA-H = 2 |
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| NFPA-F = 0 |
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| NFPA-R = 0 |
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}} |
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|Section4={{Chembox Related |
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| OtherFunction_label = alkanols |
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| OtherFunction = {{unbulleted list|]|]|]|]|]|]|]|]}} |
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| OtherCompounds = ] |
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}} |
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}} |
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'''Bis-tris methane''', also known as '''BIS-TRIS''' or '''BTM''', is a ] used in ]. Bis-tris methane is an organic tertiary ] with labile protons having a ] of 6.46 at 25 °C. It is an effective buffer between the ] 5.8 and 7.2. Bis-tris methane binds strongly to Cu and Pb ions as well as, weakly, to Mg, Ca, Mn, Co, Ni, Zn and Cd.<ref>{{Cite journal|last1=Ferreira|first1=Carlos M. H.|last2=Pinto|first2=Isabel S. S.|last3=Soares|first3=Eduardo V.|last4=Soares|first4=Helena M. V. M.|date=2015|title=(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions – a review|url=http://xlink.rsc.org/?DOI=C4RA15453C|journal=RSC Advances|language=en|volume=5|issue=39|pages=30989–31003|doi=10.1039/c4ra15453c|issn=2046-2069|hdl=10400.22/7404|hdl-access=free}}</ref> |
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==See also== |
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*] |
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*] |
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*] |
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==References== |
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{{reflist}} |
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{{DEFAULTSORT:Bis-Tris Methane}} |
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] |
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] |
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] |
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{{amine-stub}} |