Revision as of 23:17, 27 November 2011 editThe chemistds (talk | contribs)Extended confirmed users5,761 edits added CSID, (Std)InChI & (Std)InChIKey← Previous edit |
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{{chembox |
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{{chembox |
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| Verifiedfields = changed |
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| verifiedrevid = 404808986 |
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| Watchedfields = changed |
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| verifiedrevid = 462806316 |
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| Name = Butein |
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| Name = Butein |
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| ImageFile = Butein.svg |
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| ImageFile = Butein.svg |
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| ImageSize = 250px |
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| ImageSize = 250px |
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| ImageName = Chemical structure of butein |
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| ImageName = Chemical structure of butein |
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| PIN = 2′,3,4,4′-Tetrahydroxychalcone |
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| IUPACName = (''E'')-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one |
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| OtherNames = 2',3,4,4'-Tetrahydroxychalcone<br>2',4',3,4-Tetrahydroxychalcone<br>3,4,2',4'-Tetrahydroxychalcone<br>2′,4′,3,4-Tetrahydroxychalcone |
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| OtherNames = (2''E'')-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one<br>2′,4′,3,4-Tetrahydroxychalcone<br>3,4,2′,4′-Tetrahydroxychalcone |
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|Section1= {{Chembox Identifiers |
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|Section1={{Chembox Identifiers |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo = 487-52-5 |
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| CASNo = 487-52-5 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| CASNo_Ref = |
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| CASOther = 21849-70-7 |
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| UNII = 4WVS5M0LGF |
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| PubChem = 5281222 |
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| PubChem = 5281222 |
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| KEGG = C08578 |
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| ChEBI = 3237 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 128000 |
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| ChEMBL = 128000 |
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| SMILES = C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O |
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| SMILES = C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 4444634 |
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| ChemSpiderID = 4444634 |
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| InChI = 1/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ |
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| InChI = 1/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ |
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| InChIKey = AYMYWHCQALZEGT-ORCRQEGFBV |
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| InChIKey = AYMYWHCQALZEGT-ORCRQEGFBV |
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| StdInChI = 1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = AYMYWHCQALZEGT-ORCRQEGFSA-N |
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| StdInChI = 1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = AYMYWHCQALZEGT-ORCRQEGFSA-N |
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| MeSHName = |
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|Section2= {{Chembox Properties |
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|Section2={{Chembox Properties |
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| C=15 | H=12 | O=5 |
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| Formula = C<sub>15</sub>H<sub>12</sub>O<sub>5</sub> |
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| MolarMass = 272.25 g/mol |
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| ExactMass = 272.068473 u |
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| Appearance = |
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| Appearance = |
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| Density = |
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| Density = |
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| MeltingPt = <!-- °C --> |
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| MeltingPt = |
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| BoilingPt = <!-- °C --> |
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| BoilingPt = |
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| Solubility = |
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| Solubility = |
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'''Butein''' is a ]. It can be found in '']'' (or formerly ''Rhus verniciflua''). It has ], ] and ]s inhibitory effects<ref name="pmid18670102">{{cite journal |author=Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH |title=Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts |journal=Biol. Pharm. Bull. |volume=31 |issue=8 |pages=1626–30 |year=2008 |month=August |pmid=18670102 |doi= 10.1248/bpb.31.1626|url=http://joi.jlc.jst.go.jp/JST.JSTAGE/bpb/31.1626?from=PubMed}}</ref>. It is also a ], a chemical compound having an effect on sirtuins, a group of enzymes that use NAD<sup>+</sup> to remove acetyl groups from proteins. |
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'''Butein''' is a ] of the ]s. It can be found in '']'' (or formerly ''Rhus verniciflua''), '']'', '']'' ('']'') and '']''.<ref>Semwal, R. B., Semwal, D. K., Combrinck, S., & Viljoen, A. (2015). Butein: From ancient traditional remedy to modern nutraceutical. Phytochemistry Letters, 11, 188-201. {{doi|10.1016/j.phytol.2014.12.014}}</ref> It has ], ] and ]s inhibitory effects.<ref name="pmid18670102">{{cite journal |vauthors=Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH |title=Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts |journal=Biol. Pharm. Bull. |volume=31 |issue=8 |pages=1626–30 |date=August 2008 |pmid=18670102 |doi= 10.1248/bpb.31.1626|doi-access=free }}</ref> It is also a ], a chemical compound having an effect on sirtuins, a group of enzymes that use NAD<sup>+</sup> to remove acetyl groups from proteins. Buteins possess a high ability to inhibit aromatase process in the human body, for this reason, the use of these compounds in the treatment of ] on the estrogen ground has been explored.<ref>Wang Y. "" Life Sci. 2005 May 20;77(1):39-51.</ref> The first attempts of sport pro-hormone supplementation with the use of buteins took place in Poland.<ref>S.Amboziak " 09.2012</ref>{{rs|date=March 2024}} |
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==References== |
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==References== |
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