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C55-isoprenyl pyrophosphate: Difference between revisions

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'''C55-isoprenyl pyrophosphate''' ('''undecaprenyl pyrophosphate'''; C55-PP) is an essential molecule involved in construction of the bacterial ] ].<ref>{{cite journal|first1=K. John |last1=Stone|first2= Jack L. |last2=Strominger|title=Mechanism of Action of Bacitracin: Complexation with Metal Ion and C55-Isoprenyl Pyrophosphate|journal=PNAS|volume=68|issue=12|date=December 1971|pages=3223–3227|pmid=4332017|doi=10.1073/pnas.68.12.3223|pmc=389626|bibcode=1971PNAS...68.3223S|doi-access=free}}</ref> It is a receptor found in the ] that allows glycan tetrapeptide monomers synthesized in the cell ] to translocate to the periplasmic space.<ref name="carrier">{{cite journal |last1=Manat |first1=Guillaume |last2=Roure |first2=Sophie |last3=Auger |first3=Rodolphe |last4=Bouhss |first4=Ahmed |last5=Barreteau |first5=Hélène |last6=Mengin-Lecreulx |first6=Dominique |last7=Touzé |first7=Thierry |title=Deciphering the Metabolism of Undecaprenyl-Phosphate: The Bacterial Cell-Wall Unit Carrier at the Membrane Frontier |journal=Microbial Drug Resistance |date=June 2014 |volume=20 |issue=3 |pages=199–214 |doi=10.1089/mdr.2014.0035}}</ref> '''C55-isoprenyl pyrophosphate''' (also known as '''undecaprenyl pyrophosphate''' or '''C55-PP''') is an essential molecule involved in the construction of the bacterial ] ].<ref>{{cite journal|first1=K. John |last1=Stone|first2= Jack L. |last2=Strominger|title=Mechanism of Action of Bacitracin: Complexation with Metal Ion and C55-Isoprenyl Pyrophosphate|journal=PNAS|volume=68|issue=12|date=December 1971|pages=3223–3227|pmid=4332017|doi=10.1073/pnas.68.12.3223|pmc=389626|bibcode=1971PNAS...68.3223S|doi-access=free}}</ref> It is a receptor found in the ] allowing ] ] ] synthesized in the cell ] to ] to the ].<ref name="carrier">{{cite journal |last1=Manat |first1=Guillaume |last2=Roure |first2=Sophie |last3=Auger |first3=Rodolphe |last4=Bouhss |first4=Ahmed |last5=Barreteau |first5=Hélène |last6=Mengin-Lecreulx |first6=Dominique |last7=Touzé |first7=Thierry |title=Deciphering the Metabolism of Undecaprenyl-Phosphate: The Bacterial Cell-Wall Unit Carrier at the Membrane Frontier |journal=Microbial Drug Resistance |date=June 2014 |volume=20 |issue=3 |pages=199–214 |doi=10.1089/mdr.2014.0035|pmid=24799078 |pmc=4050452 }}</ref>


A related compound is C55-P (undecaprenyl phosphate), differing by having one fewer phosphate group. It is produced from C55-PP by reaction ], typically catalyzed by UppP/BacA. C55-P is recycled back into C55-PP later in the process.<ref name="carrier"/> C55-P (]) is a related compound, containing one fewer ]. It is produced from C55-PP by reaction ], typically catalyzed by UppP/BacA. C55-P is recycled back into C55-PP later in the process. C55-OH is known as ].<ref name="carrier"/>


==References== ==References==