Revision as of 20:27, 10 November 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChemSpiderID', 'ChEBI', 'KEGG', 'StdInChI', 'StdInChIKey', 'CASNo').← Previous edit |
Latest revision as of 00:39, 9 March 2022 edit undoFswitzer4 (talk | contribs)Extended confirmed users10,572 editsm Added/Verified UNII and Verified CAS |
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| Verifiedfields = changed |
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| Verifiedfields = changed |
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| Watchedfields = changed |
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| Watchedfields = changed |
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| verifiedrevid = 399710172 |
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| verifiedrevid = 460021204 |
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| ImageFile = Carveol.png |
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| ImageFileL1 = 1R,5R-Carveol.png |
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| ImageCaptionL1 = (1''R'',5''R'')-Carveol<br>((–)-''cis'') |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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| ImageFileR1 = 1S,5R-Carveol.png |
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| ImageSize = 121 |
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| ImageCaptionR1 = (1''S'',5''R'')-Carveol<br>((–)-''trans'') |
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| ImageName = Stereo skeletal formula of carveol ((1S,5R)-5-yl,-1-ol) |
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| ImageFileL2 = 1R,5S-Carveol.png |
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| IUPACName = 2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol |
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| ImageCaptionL2 = (1''R'',5''S'')-Carveol<br>((+)-''trans'') |
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| SystematicName = 2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol<ref>{{Cite web|title = Carveol|url = https://www.ebi.ac.uk/chebi/searchId.do?chebiId=23046|work = Chemical Entities of Biological Interest|location = UK|publisher =European Bioinformatics Institute}}</ref> |
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| ImageFileR2 = 1S,5S-Carveol.png |
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| OtherNames = Mentha-6,8-dien-2-ol |
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| ImageCaptionR2 = (1''S'',5''S'')-Carveol<br>((+)-''cis'') |
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| Section1 = {{Chembox Identifiers |
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| PIN = 2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol |
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| CASNo = <!-- blanked - oldvalue: 99-48-9 --> |
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| OtherNames = 2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol<br />Mentha-6,8-dien-2-ol |
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| CASNo_Ref = {{cascite|correct|??}} |
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|Section1={{Chembox Identifiers |
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| PubChem = 7438 |
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| IUPHAR_ligand = 6417 |
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| PubChem_Ref = {{Pubchemcite|correct|PubChem}} |
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| PubChem1 = 2724032 |
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| CASNo = 99-48-9 |
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| PubChem1_Ref = {{Pubchemcite|correct|PubChem}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| PubChem1_Comment = (5''R'') |
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| PubChem2 = 11084068 |
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| UNII = 1L9KXT85R9 |
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| PubChem = 7438 |
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| PubChem2_Ref = {{Pubchemcite|correct|PubChem}} |
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| PubChem1 = 2724032 |
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| PubChem2_Comment = (5''S'') |
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| PubChem1_Comment = (5''R'') |
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| PubChem3 = 330573 |
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| PubChem2 = 11084068 |
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| PubChem3_Ref = {{Pubchemcite|correct|PubChem}} |
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| PubChem3_Comment = (1''R'',5''R'') |
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| PubChem2_Comment = (5''S'') |
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| PubChem4 = 443178 |
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| PubChem3 = 330573 |
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| PubChem3_Comment = (1''R'',5''R'') |
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| PubChem4_Ref = {{Pubchemcite|correct|PubChem}} |
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| PubChem4_Comment = (1''R'',5''S'') |
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| PubChem4 = 443178 |
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| PubChem4_Comment = (1''R'',5''S'') |
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| ChemSpiderID = 391450 |
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| ChemSpiderID = 7160 |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID1 = 2006207 |
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| ChemSpiderID1 = 2006207 |
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| ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID1_Comment = (5''R'') |
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| ChemSpiderID1_Comment = (5''R'') |
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| ChemSpiderID2 = 9259214 |
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| ChemSpiderID2 = 9259214 |
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| ChemSpiderID2_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID2_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID2_Comment = (5''S'') |
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| ChemSpiderID2_Comment = (5''S'') |
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| ChemSpiderID3 = 292842 |
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| ChemSpiderID3 = 292842 |
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| ChemSpiderID3_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID3_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID3_Comment = (1''R'',5''R'') |
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| ChemSpiderID3_Comment = (1''R'',5''R'') |
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| ChemSpiderID4 = 391450 |
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| ChemSpiderID4 = 391450 |
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| ChemSpiderID4_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID4_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID4_Comment = (1''R'',5''S'') |
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| ChemSpiderID4_Comment = (1''R'',5''S'') |
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| EINECS = 202-757-4 |
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| EINECS = 202-757-4 |
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| KEGG = <!-- blanked - oldvalue: C11395 --> |
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| KEGG = C11395 |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
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| MeSHName = Carveol |
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| MeSHName = Carveol |
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| ChEMBL = 1385229 |
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| ChEBI_Ref = {{ebicite|changed|EBI}} |
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| ChEBI = 15388 |
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| ChEMBL1 = 1907992 |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| RTECS = OS8400000 |
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| Beilstein = 1861032 |
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| ChEMBL5 = 1908058 |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| 3DMet = B04241 |
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| ChEBI = 23046 |
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| SMILES = CC(=C)C1CC=C(C)C(O)C1 |
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| ChEBI1=227 |
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| SMILES1 = OC1C(=C/CC(/C(=C)C)C1)\C |
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| ChEBI2=232 |
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| StdInChI = 1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3/t9-,10+/m0/s1 |
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| RTECS = OS8400000 |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| Beilstein = 1861032 |
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| InChI = 1/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3 |
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| 3DMet = B04334 |
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| StdInChIKey = BAVONGHXFVOKBV-VHSXEESVSA-N |
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| SMILES = CC(=C)C1CC=C(C)C(O)C1 |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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| SMILES1 = OC1C(=C/CC(/C(=C)C)C1)\C |
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| StdInChI = 1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3 |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| InChI = 1/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3 |
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| StdInChIKey = BAVONGHXFVOKBV-UHFFFAOYSA-N |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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}} |
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| Section2 = {{Chembox Properties |
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|Section2={{Chembox Properties |
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| C = 10 |
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| C=10 | H=16 | O=1 |
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| Density = 0.958 g cm<sup>−3</sup> |
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| H = 16 |
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| BoilingPtC = 226 to 227 |
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| O = 1 |
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| ExactMass = 152.120115134 g mol<sup>-1</sup> |
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| Density = 0.958 g cm<sup>-3</sup> |
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| BoilingPtCL = 226 |
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| BoilingPtCH = 227 |
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| Section3 = {{Chembox Hazards |
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|Section3={{Chembox Hazards |
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| EUClass = {{Hazchem Xi}} |
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| GHSPictograms = {{GHS07}} |
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| GHSSignalWord = Warning |
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| RPhrases = {{R36/37/38}} |
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| SPhrases = {{S26}} {{S37/39}} |
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| HPhrases = {{H-phrases|315|319|335}} |
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| PPhrases = {{P-phrases|261|264|271|280|302+352|304+340|305+351+338|312|321|332+313|337+313|362|403+233|405|501}} |
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| NFPA-H = 1 |
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| NFPA-F = 1 |
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| NFPA-H = 1 |
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| NFPA-R = 0 |
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| NFPA-F = 1 |
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| NFPA-R = 0 |
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| FlashPt = {{convert|98|C|F}} |
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| FlashPtC = 98 |
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'''Carveol''' is a natural unsaturated, monocyclic mono] ] that is a constituent of ] essential oil in the form of ''cis''-(−)-carveol. It is a colorless fluid soluble in water and oils, but insoluble in water and has an odor and flavor that resemble those of spearmint and ]. Consequently, it is used as a fragrance in cosmetics and as a flavor additive in the food industry. |
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'''Carveol''' is a natural unsaturated, monocyclic mono] ] that is a constituent of ] essential oil in the form of ''cis''-(−)-carveol. It is a colorless fluid soluble in oils, but insoluble in water and has an odor and flavor that resemble those of spearmint and ]. Consequently, it is used as a fragrance in cosmetics and as a flavor additive in the food industry. |
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It has been found to exhibit chemoprevention of mammary carcinogenesis (prevents ]).<ref>{{cite journal | pmid = 1638695 | year = 1992 | last1 = Crowell | first1 = PL | last2 = Kennan | first2 = WS | last3 = Haag | first3 = JD | last4 = Ahmad | first4 = S | last5 = Vedejs | first5 = E | last6 = Gould | first6 = MN | title = Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene | volume = 13 | issue = 7 | pages = 1261–4 | journal = Carcinogenesis | doi=10.1093/carcin/13.7.1261}}</ref> |
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It has been found to exhibit chemoprevention of mammary carcinogenesis (prevents ]).<ref>{{cite journal | pmid = 1638695 | year = 1992 | last1 = Crowell | first1 = PL | last2 = Kennan | first2 = WS | last3 = Haag | first3 = JD | last4 = Ahmad | first4 = S | last5 = Vedejs | first5 = E | last6 = Gould | first6 = MN | title = Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene | volume = 13 | issue = 7 | pages = 1261–4 | journal = Carcinogenesis | doi=10.1093/carcin/13.7.1261}}</ref> |
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An ''alpha''-''trans''-dihydroxy ] ((1''R'',2''R'',6''S'')-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol) possesses potent antiparkinsonian activity in animal models.<ref>{{cite journal | doi = 10.1021/jm2001579 | title = Highly Potent Activity of (1R,2R,6S)-3-Methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in Animal Models of Parkinson's Disease | year = 2011 | last1 = Ardashov | first1 = Oleg V. | last2 = Pavlova | first2 = Alla V. | last3 = Il’Ina | first3 = Irina V. | last4 = Morozova | first4 = Ekaterina A. | last5 = Korchagina | first5 = Dina V. | last6 = Karpova | first6 = Elena V. | last7 = Volcho | first7 = Konstantin P. | last8 = Tolstikova | first8 = Tat’Yana G. | last9 = Salakhutdinov | first9 = Nariman F. | journal = Journal of Medicinal Chemistry | volume = 54 | issue = 11 | pages = 3866–3874 | pmid = 21534547}}</ref> |
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An ''alpha''-''trans''-dihydroxy ], (1''R'',2''R'',6''S'')-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol, possesses potent ]ian activity in animal models.<ref>{{cite journal | doi = 10.1021/jm2001579 | title = Highly Potent Activity of (1''R'',2''R'',6''S'')-3-Methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in Animal Models of Parkinson's Disease | year = 2011 | last1 = Ardashov | first1 = Oleg V. | last2 = Pavlova | first2 = Alla V. | last3 = Il’Ina | first3 = Irina V. | last4 = Morozova | first4 = Ekaterina A. | last5 = Korchagina | first5 = Dina V. | last6 = Karpova | first6 = Elena V. | last7 = Volcho | first7 = Konstantin P. | last8 = Tolstikova | first8 = Tat’Yana G. | last9 = Salakhutdinov | first9 = Nariman F. | journal = Journal of Medicinal Chemistry | volume = 54 | issue = 11 | pages = 3866–3874 | pmid = 21534547 }}</ref> |
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==References== |
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==References== |
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{{Reflist}} |
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{{Reflist}} |
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