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Latest revision as of 13:41, 30 January 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,119 edits Importing Wikidata short description: "Anti cold and flu preparation"Tag: Shortdesc helper |
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{{Short description|Anti cold and flu preparation}} |
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{{Drugbox |
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{{Drugbox |
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<!--Combo data--> |
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<!--Combo data--> |
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| verifiedrevid = 452557464 |
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| type = combo |
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| type = combo |
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| component1 = Guaifenesin |
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| component1 = Guaifenesin |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = |
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| tradename = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_AU = B2 |
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| pregnancy_US = C |
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| pregnancy_US = N |
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| pregnancy_category = |
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| pregnancy_category = |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = OTC |
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| legal_US = OTC |
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| legal_status = |
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| legal_status = |
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| routes_of_administration = Oral |
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| routes_of_administration = ] |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number = |
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| CAS_number = 55-38-9 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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The combination of the drugs '''guaifenesin''' and '''phenylephrine''' is a preparation against the symptoms of cold, flu and allergy. Guaifenesine is an ], phenylephrine is a ]. The drug is sold under the trade name '''Entex''', among others. |
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'''Guaifenesin/phenylephrine''' is a combination of the drugs ] and ] and is a preparation against the symptoms of cold, flu and allergy. Guaifenesine is an ], phenylephrine is a ]. The drug is sold under the brand name '''Entex''' and as generic brands. Entex La is 400 mg guaifenesin and 30 mg phenylephrine hydrochloride. Entex Pse is 600 mg guaifenesin and 120 mg phenylephrine hydrochloride. Both are extended release products, meaning that the non-active ingredients are chosen to dissolve slowly to provide a prolonged therapeutic effect.{{citation needed|date=January 2021}} |
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__TOC__ |
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==Guaifenesin== |
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{{Main|Guaifenesin}} |
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Guaifenesin is an oral ] used to try to help ] ] from the ]s.<ref name=AHFS2019>{{cite web |title=Guaifenesin Monograph for Professionals |url=https://www.drugs.com/monograph/guaifenesin.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |access-date=25 March 2019 |language=en}}</ref> It is often used in combination with other medications.<ref name=AHFS2019/> It is believed to work by making airway secretions more liquid.<ref name=AHFS2019/> Side effects may include ], sleepiness, skin rash, and nausea.<ref>{{cite web| title = Guaifenesin| url = https://www.drugs.com/ppa/guaifenesin-glyceryl-guaiacolate.html| publisher = Drugs.com| access-date = 2019-03-25}}</ref> Guaifenesin has been used medically since at least 1933.<ref>{{cite book | vauthors = Riviere JE, Papich MG |title=Veterinary Pharmacology and Therapeutics |date=2013 |publisher=John Wiley & Sons |isbn=9781118685907 |page=287 |url=https://books.google.com/books?id=xAPa4WDzAnQC&pg=PA287 |language=en}}</ref> It is available as a ] and an ].<ref name=AHFS2019/><ref>{{cite book | vauthors = Weiner CP, Rope K |title=The Complete Guide to Medications During Pregnancy and Breastfeeding: Everything You Need to Know to Make the Best Choices for You and Your Baby |date=2013 |publisher=St. Martin's Press |isbn=9781250037206 |page=PT282 |url=https://archive.org/details/completeguidetom0000wein_t9k5 |url-access=registration |language=en}}</ref> |
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==Phenylephrine== |
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{{Main|Phenylephrine}} |
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Phenylephrine is an oral medication primarily used as a decongestant.<ref name=AHFS>{{cite web |title=Phenylephrine Hydrochloride Monograph for Professionals |url=https://www.drugs.com/monograph/phenylephrine-hydrochloride.html |website=Drugs.com |publisher=AHFS |access-date=10 January 2019}}</ref><ref name=BNF76>{{cite book|title=British national formulary : BNF 76|date=2018|publisher=Pharmaceutical Press|isbn=9780857113382|pages=188–189|edition=76, 1140}}</ref> It is a selective ] ] which results in the ] of both ] and ].<ref name=AHFS/> Common side effects include nausea, headache, and anxiety.<ref name=AHFS/> Phenylephrine was patented in 1927 and came into medical use in 1938.<ref>{{cite book| vauthors = Fischer J, Ganellin CR |title=Analogue-based Drug Discovery|date=2006|publisher=John Wiley & Sons|isbn=9783527607495|page=541|url=https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA541}}</ref> It is available as a generic medication.<ref name=BNF76/> |
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== References == |
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{{reflist}} |
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{{DEFAULTSORT:Guaifenesin Phenylephrine}} |
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