| Revision as of 12:08, 13 November 2010 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: StdInChI StdInChIKey.← Previous edit |
Latest revision as of 16:14, 21 October 2024 edit undoJWBE (talk | contribs)Extended confirmed users10,126 edits removed Category:Phenols; added Category:Hydroxyarenes using HotCat |
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{{Short description|Chemical compound}} |
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{{more citations needed|date=January 2021}} |
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{{Drugbox |
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{{Drugbox |
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| Watchedfields = changed |
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| verifiedrevid = 390504631 |
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| verifiedrevid = 443864211 |
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| IUPAC_name = 7-Hydroxy-4-methylchromen-2-one |
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| IUPAC_name = 7-Hydroxy-4-methylchromen-2-one |
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| image = Hymecromone.png |
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| image = Hymecromone.png |
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| synonyms = 4-Methylumbelliferone |
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<!--Clinical data--> |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| tradename = |
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| Drugs.com = {{drugs.com|international|hymecromone}} |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category = |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 90-33-5 |
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| ATC_prefix = A05 |
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| ATC_suffix = AX02 |
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| PubChem = 5280567 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB07118 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 4444190 |
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| ChemSpiderID = 4444190 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 3T5NG4Q468 |
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| UNII = 3T5NG4Q468 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| InChI = 1/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 |
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| KEGG = D00170 |
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| smiles = O=C/2Oc1cc(O)ccc1\C(=C\2)C |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| InChIKey = HSHNITRMYYLLCV-UHFFFAOYAZ |
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| ChEBI = 17224 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 12208 |
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<!--Chemical data--> |
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| C=10 | H=8 | O=3 |
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| smiles = CC1=CC(=O)OC2=C1C=CC(=C2)O |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 |
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| StdInChI = 1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = HSHNITRMYYLLCV-UHFFFAOYSA-N |
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| StdInChIKey = HSHNITRMYYLLCV-UHFFFAOYSA-N |
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| synonyms = 4-Methylumbelliferone |
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| CAS_number = 90-33-5 |
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| ATC_prefix = A05 |
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| ATC_suffix = AX02 |
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| PubChem = 5280567 |
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| DrugBank = |
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| C=10|H=8|O=3 |
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| molecular_weight = 176.17 g/mol |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category= |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| routes_of_administration = |
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}} |
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}} |
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'''Hymecromone''' (4-methylumbelliferone) is a drug used in ] therapy. It is used as ] and ] drugs and as a standard for the fluorometric determination of enzyme activity.<ref name="pmid7390976">{{cite journal | vauthors = Yang Y, Hamaguchi K | title = Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotrioside catalyzed by hen and turkey lysozymes. pH dependence of the kinetics constants | journal = Journal of Biochemistry | volume = 87 | issue = 4 | pages = 1003–14 | date = April 1980 | pmid = 7390976 | doi = 10.1093/oxfordjournals.jbchem.a132833 }}</ref> |
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'''Hymecromone''' (4-methylumbelliferone) is a drug used in bile therapy. |
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(organic chemistry) C10H8O3 A crystalline substance with a melting point of 194-195°C; soluble in methanol and glacial acetic acid; used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity. |
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Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in ] and ]. |
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==See also== |
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*] |
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*] |
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==References== |
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{{Reflist}} |
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{{Bile and liver therapy}} |
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{{Bile and liver therapy}} |
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{{coumarin}} |
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{{coumarin}} |
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] |
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] |
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] |
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] |
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{{gastrointestinal-drug-stub}} |
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{{gastrointestinal-drug-stub}} |
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] |
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] |
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