| Revision as of 07:52, 13 August 2010 editSnubcube (talk | contribs)Extended confirmed users638 edits Replace png with svg← Previous edit |
Latest revision as of 17:37, 11 January 2023 edit undoFfffrr (talk | contribs)Extended confirmed users99,439 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper |
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{{Short description|Chemical compound}} |
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{{Drugbox| |
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{{Drugbox |
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|IUPAC_name = ''N''--''N'''-(2-{thio}ethyl)guanidine |
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| Verifiedfields = changed |
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| image=Impromidine.svg |
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| Watchedfields = changed |
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| CAS_number=55273-05-7 |
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| verifiedrevid = 378676793 |
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| ATC_prefix=none |
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| IUPAC_name = 2--1-ethyl]guanidine |
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| image = Impromidine.svg |
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| PubChem= 41376 |
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| width = 260 |
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| image2 = Impromidine 3D.png |
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<!--Clinical data--> |
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| tradename = |
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| routes_of_administration = |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 55273-05-7 |
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| ATC_prefix = none |
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| PubChem = 41376 |
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| IUPHAR_ligand = 1226 |
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| IUPHAR_ligand = 1226 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank= |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| smiles = Cc2ncnc2CSCCNC(N)=NCCCc1cncn1 |
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| UNII = 931L4X5WMM |
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| C=14 | H=23 | N=7 | S=1 |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| molecular_weight = 321.44 g/mol |
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| ChEMBL = 12608 |
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| bioavailability= |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| metabolism = |
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| ChemSpiderID = 37757 |
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| elimination_half-life= |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| excretion = |
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| StdInChI = 1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18) |
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| pregnancy_category = |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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| legal_status = |
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| StdInChIKey = MURRAGMMNAYLNA-UHFFFAOYSA-N |
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<!--Chemical data--> |
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| C=14 | H=23 | N=7 | S=1 |
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| smiles = Cc1cnc1CSCCNC(=N)NCCCc2ccn2 |
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'''Impromidine''' (]) is a highly potent and specific ] H<sub>2</sub> receptor ].<ref>{{cite journal |author=Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A |title=Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors |url=http://www.nature.com/nature/journal/v276/n5686/abs/276403a0.html |journal=] |volume=276 |issue=5686 |pages=403–5 |year=1978 |pmid=714166 |doi=10.1038/276403a0}}</ref> |
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'''Impromidine''' (]) is a highly potent and specific histamine ] ].<ref>{{cite journal |vauthors=Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A |title=Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors |journal=] |volume=276 |issue=5686 |pages=403–5 |year=1978 |pmid=714166 |doi=10.1038/276403a0|s2cid=4242863 }}</ref> |
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It has been used diagnostically as a gastric secretion indicator. |
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It has been used diagnostically as a gastric secretion indicator. |
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See ]. |
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== See also == |
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* ] |
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==References== |
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==References== |
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<references/> |
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<references/> |
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{{pharma-stub}} |
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{{Histaminergics}} |
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{{Histaminergics}} |
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] |
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{{gastrointestinal-drug-stub}} |