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|ImageFile=Iodophenpropit.png |
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| verifiedrevid = 400753856 |
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|IUPACName=3-(1''H''-imidazol-5-yl)propyl ''N'''-imidothiocarbamate |
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| ImageFile = Iodophenpropit.svg |
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|OtherNames=1--N'-formamidine |
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| ImageSize = 240 |
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|Section1={{Chembox Identifiers |
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| IUPACName = 3-(1''H''-imidazol-5-yl)propyl ''N'''-imidothiocarbamate |
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| CASNo=143407-29-8 |
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| OtherNames = 1--''N'''-formamidine |
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| PubChem=3035746 |
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| SMILES=C1=CC(=CC=C1CCN=C(N)SCCCC2=CN=CN2)I |
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| Section1 = {{Chembox Identifiers |
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| MeSHName=Iodophenpropit |
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| CASNo_Ref = {{cascite|correct|??}} |
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| CASNo=145196-88-9 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 3SH45L9H3Z |
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| PubChem=3035746 |
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| ChemSpiderID=2299913 |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| ChEMBL = 498770 |
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| SMILES=C1=CC(=CC=C1CCN=C(N)SCCCC2=CN=CN2)I |
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| MeSHName=Iodophenpropit |
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|Section2={{Chembox Properties |
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| Formula=C<sub>15</sub>H<sub>19</sub>IN<sub>4</sub>S |
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| Formula = C<sub>15</sub>H<sub>19</sub>IN<sub>4</sub>S |
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| MolarMass=414.30763 |
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| MolarMass = 414.30763 g/mol |
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'''Iodophenpropit''' is a ] which binds selectively to the ] subtype. Its <sup>125</sup>I ] form is used for mapping the distribution of H<sub>3</sub> receptors in the body.<ref>{{cite journal | last1 = Jansen | first1 = FP | last2 = Wu | first2 = TS | last3 = Voss | first3 = HP | last4 = Steinbusch | first4 = HW | last5 = Vollinga | first5 = RC | last6 = Rademaker | first6 = B | last7 = Bast | first7 = A | last8 = Timmerman | first8 = H | title = Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain | journal = British journal of pharmacology | volume = 113 | issue = 2 | pages = 355–62 | year = 1994 | pmid = 7834183 | pmc = 1510107 }}</ref><ref>{{cite journal | last1 = Jansen | first1 = FP | last2 = Mochizuki | first2 = T | last3 = Maeyama | first3 = K | last4 = Leurs | first4 = R | last5 = Timmerman | first5 = H | title = Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit | journal = Naunyn-Schmiedeberg's archives of pharmacology | volume = 362 | issue = 1 | pages = 60–7 | year = 2000 | pmid = 10935534 }}</ref> |
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'''Iodophenpropit''' is a ] which binds selectively to the ]. Its <sup>125</sup>I ] form has been used for mapping the distribution of H<sub>3</sub> receptors in animal studies.<ref>{{cite journal | last1 = Jansen | first1 = FP | last2 = Wu | first2 = TS | last3 = Voss | first3 = HP | last4 = Steinbusch | first4 = HW | last5 = Vollinga | first5 = RC | last6 = Rademaker | first6 = B | last7 = Bast | first7 = A | last8 = Timmerman | first8 = H | title = Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain | journal = ] | volume = 113 | issue = 2 | pages = 355–62 | year = 1994 | pmid = 7834183 | pmc = 1510107 | doi=10.1111/j.1476-5381.1994.tb16995.x}}</ref><ref>{{cite journal | last1 = Jansen | first1 = FP | last2 = Mochizuki | first2 = T | last3 = Maeyama | first3 = K | last4 = Leurs | first4 = R | last5 = Timmerman | first5 = H | title = Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | volume = 362 | issue = 1 | pages = 60–7 | year = 2000 | pmid = 10935534 | doi = 10.1007/s002100000227 | s2cid = 21293180 }}</ref> |
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==References== |
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