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| Verifiedfields = changed |
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| verifiedrevid = 363253909 |
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| Watchedfields = changed |
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| Name = Isopropyl myristate |
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| verifiedrevid = 442524832 |
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| Reference = <ref></ref> |
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| ImageFile = Isopropyl myristate.png |
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| Name = Isopropyl myristate |
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| Reference = <ref>{{Cite web |title=SAFETY DATA SHEET |url=https://www.fishersci.com/store/msds?partNumber=AC412851000&countryCode=US&language=en |access-date=2024-05-05 |website=Fisher Scientific |publication-date=2009-09-22}}</ref> |
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| ImageSize = 200px |
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| ImageName = Isopropyl myristate |
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| ImageFile = Isopropyl myristate.png |
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| ImageSize = 200px |
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| IUPACName = Propan-2-yl tetradecanoate |
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| ImageName = Isopropyl myristate |
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| OtherNames = Tetradecanoic acid, 1-methylethyl ester<br />Myristic acid isopropyl ester |
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| PIN = Propan-2-yl tetradecanoate |
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| Section1 = {{Chembox Identifiers |
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| OtherNames = Tetradecanoic acid, 1-methylethyl ester<br />Myristic acid isopropyl ester |
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| SMILES = CCCCCCCCCCCCCC(=O)OC(C)C |
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|Section1={{Chembox Identifiers |
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| CASNo_Ref = {{cascite}} |
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| SMILES = CCCCCCCCCCCCCC(=O)OC(C)C |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo = 110-27-0 |
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| CASNo = 110-27-0 |
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| EINECS = 203-751-4 |
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| ChEMBL = 207602 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| RTECS = XB8600000 |
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| UNII = 0RE8K4LNJS |
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| EINECS = 203-751-4 |
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| RTECS = XB8600000 |
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| PubChem = 8042 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 7751 |
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| InChI = 1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
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| InChIKey = AXISYYRBXTVTFY-UHFFFAOYAN |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| StdInChI = 1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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| StdInChIKey = AXISYYRBXTVTFY-UHFFFAOYSA-N |
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| MeSHName = C008205 |
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| ChEBI = |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D02296 |
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| Section2 = {{Chembox Properties |
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|Section2={{Chembox Properties |
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| C=17 | H=34 | O=2 |
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| Formula = C<sub>17</sub>H<sub>34</sub>O<sub>2</sub> |
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| Appearance = |
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| MolarMass = 270.451 g/mol |
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| Density = 0.85 g/cm<sup>3</sup> |
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| Appearance = |
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| Solubility = |
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| Density = 0.85 g/cm³, liquid |
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| Solubility = |
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| MeltingPt = |
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| BoilingPtC = 167 |
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| MeltingPt = |
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| BoilingPt = 167 °C (9 mmHg) |
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| BoilingPt_notes = at 9 mmHg |
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| pKa = |
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| Section3 = {{Chembox Structure |
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|Section3={{Chembox Structure |
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| MolShape = |
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| Dipole = |
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| Dipole = |
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| Section7 = {{Chembox Hazards |
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|Section7={{Chembox Hazards |
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| ExternalMSDS = |
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| ExternalSDS = |
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| MainHazards = |
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| MainHazards = |
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| NFPA-H = 0 |
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| FlashPt = |
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| RPhrases = {{R38}} |
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| NFPA-F = 1 |
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| NFPA-R = 0 |
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| SPhrases = {{S24/25}} |
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| FlashPt = |
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| Section8 = {{Chembox Related |
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|Section8={{Chembox Related |
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| OtherAnions = |
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| OtherAnions = |
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| OtherCations = |
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'''Isopropyl myristate''' is the ] of ] and ]. |
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'''Isopropyl myristate''' (IPM) is the ] of ] and ]. |
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==Uses== |
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==Uses== |
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Isopropyl myristate is used in cosmetic and topical medicinal preparations where good absorption through the skin is desired. It is also used as a ]-free treatment against ] which works by dissolving the ] that covers the ] of head lice, killing them by ].<ref></ref> |
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Isopropyl myristate is a polar ] and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for ].<ref>{{Cite web |title=Anti-Lice Treatments |url=http://www.lice.ca/treatment/anti_lice_insecticide.html |access-date=2024-05-05 |website=www.lice.ca}}</ref> It is also in flea and tick killing products for pets. |
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It is also the ] component of the two-phase mouthwash, ], where it removes bacteria from the oral cavity. |
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It is used to remove bacteria from the oral cavity as the ] component of the two-phase ] product "]". |
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Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of ]. |
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Isopropyl myristate has been shown to show a comedogenic and irritability to users with acne-prone skin.<ref>http://www.skinpatico.com/Acne-Cosmetics-Acne-Causing-Ingredients.php</ref>{{Verify credibility|date=August 2011}} |
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] of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.<ref>Wen, Z.; Fang, L. and He, Z. (2009). Effect of chemical enhancers on percutaneous absorption of daphnetin in isopropyl myristate vehicle across rat skin in vitro. Drug Deliv, 16: 214-223</ref><ref>Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7</ref> |
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==References== |
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==References== |
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==External links== |
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==External links== |
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* {{HPD|94}} |
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* {{CPID|id=94}} |
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{{Cosmetics}} |
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