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{{Short description|Chemical compound}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| verifiedrevid = 443910201 |
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| Watchedfields = changed |
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| IUPAC_name = Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate |
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| verifiedrevid = 443911727 |
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| image = Kappadione.svg |
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| IUPAC_name = Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate |
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| width = 180 |
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| image = Kappadione.svg |
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| CAS_number = 131-13-5 |
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| width = 180 |
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| CAS_supplemental = <br>6700-42-1 (hexahydrate) |
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| smiles = CC1=C(C2=CC=CC=C2C(=C1)OP(=O)())OP(=O)().... |
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<!--Clinical data--> |
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| ATC_prefix = none |
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| ATC_suffix = |
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| tradename = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category = |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_status = Rx-only |
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| legal_US = Rx only, discontinued (was FDA approved) |
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| routes_of_administration = Injection |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 6700-42-1 |
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| CAS_supplemental = |
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| ATC_prefix = none |
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| ATC_suffix = |
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| PubChem = 8555 |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = 8237 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB09332 |
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| KEGG = D04908 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 2OVL75B30W |
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| UNII = 2OVL75B30W |
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| PubChem = 8555 |
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<!--Chemical data--> |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| C=11 | H=8 | Na=4 | O=8 | P=2 |
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| smiles = CC1=C(C2=CC=CC=C2C(=C1)OP(=O)())OP(=O)().... |
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| C=11|H=8|Na=4|O=8|P=2 |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| molecular_weight = 422.08 g/mol |
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| StdInChI = 1S/C11H12O8P2.4Na/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17;;;;/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17);;;;/q;4*+1/p-4 |
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| bioavailability = |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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| protein_bound = |
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| StdInChIKey = GZBACHSOZNEZOG-UHFFFAOYSA-J |
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| metabolism = |
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| elimination_half-life = |
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| excretion = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| pregnancy_category= |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = Rx-only, Discontinued (Was FDA Approved) |
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| routes_of_administration = Injection |
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}} |
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}} |
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'''Kappadione''' is a ] derivative. It was manufactured by ].<ref>{{cite web |url=http://www.medicine.org/fda/drugname/KAPPADIONE |title=Kappadione overview, medicine.org |accessdate=2008-04-14 |format= |work=}} {{Dead link|date=October 2010|bot=H3llBot}}</ref> Chemically, it is ] sodium diphosphate. |
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'''Kappadione''' is a ] derivative used for the treatment of side effects of ] such as ], prophylaxis and treatment of ], and ] due to various causes.<ref name="DrugBank" /> It was manufactured by ].<ref>{{cite web |url=http://www.medicine.org/fda/drugname/KAPPADIONE |archive-url=https://web.archive.org/web/20160303202730/http://www.medicine.org/fda/drugname/KAPPADIONE |url-status=dead |archive-date=2016-03-03 |title=Kappadione overview, medicine.org |accessdate=2008-04-14 }} </ref> Chemically, it is ] sodium diphosphate. It was approved by the US ] prior to 1982 and marketed by Lilly. It has since been discontinued and is not available in North America.<ref name="DrugBank">{{DrugBank|DB09332}}. Accessed 21 April 2021.</ref> |
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==References== |
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==References== |
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