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{{about|the biochemical ]|information about other types of mops|Mops (disambiguation)}} {{Other uses|Mops (disambiguation){{!}}Mops}}
{{chembox {{Chembox
| Verifiedfields = changed
⚫ | verifiedrevid = 407780760
| Watchedfields = changed
|ImageFile=MOPS.png
⚫ | verifiedrevid = 442344970
|ImageSize=200px
| ImageFile = Mops is.svg
|IUPACName=3-morpholinopropane-1-sulfonic acid
| PIN = 3-(Morpholin-4-yl)propane-1-sulfonic acid
|OtherNames=3-(N-morpholino)propanesulfonic acid
| OtherNames = 3-(''N''-Morpholino)propanesulfonic acid,<br />3-Morpholinopropanesulfonic acid,<br />3-''N''-Morpholino propansulfonic acid,<br />4-Morpholinepropanesulfonic acid
|Section1= {{Chembox Identifiers | Section1 = {{Chembox Identifiers
⚫ | CASNo=1132-61-2
| CASNo_Ref = {{cascite|correct|??}}
⚫ | PubChem=70807
⚫ | CASNo = 1132-61-2
⚫ | SMILES=C1COCCN1CCCS(=O)(=O)O
| CASNo_Comment = (free acid)
| CASNo2_Ref = {{cascite|unknown|CAS}}
| CASNo2 = 71119-22-7
| CASNo2_Comment = (sodium salt)
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 273BP63NV3
⚫ | PubChem = 70807
⚫ | SMILES = C1COCCN1CCCS(=O)(=O)O
| PubChem2 = 2723950
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 63972
| InChI = 1/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
| InChIKey = DVLFYONBTKHTER-UHFFFAOYAN
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = DVLFYONBTKHTER-UHFFFAOYSA-N
}} }}
|Section2= {{Chembox Properties | Section2 = {{Chembox Properties
| C=7|H=15|N=1|O=4|S=1
| Formula=C<sub>7</sub>H<sub>15</sub>NO<sub>4</sub>S
| Appearance =
| MolarMass=209.2633
| Appearance= | Density =
| Density= | MeltingPt =
| MeltingPt= | BoilingPt =
⚫ | Solubility =
| BoilingPt=
⚫ | Solubility=
}} }}
|Section3= {{Chembox Hazards | Section3 = {{Chembox Hazards
| GHSPictograms = {{GHS07}}
⚫ | MainHazards=
| GHSSignalWord = Warning
⚫ | FlashPt=
| HPhrases = {{H-phrases|315|319|335}}
| Autoignition=
| PPhrases = {{P-phrases|261|264|271|280|302+352|304+340|305+351+338|312|321|332+313|337+313|362|403+233|405|501}}
⚫ | MainHazards =
⚫ | FlashPt =
| AutoignitionPt =
| ExternalSDS =
}} }}
}} }}

'''MOPS''' is the common name for the compound '''3-(N-morpholino)propanesulfonic acid''', a ] introduced by Good et al. in the 1960s. It is a structural analog to ].<ref>{{cite journal|doi=10.1021/bi00866a011|title=Hydrogen Ion Buffers for Biological Research|year=1966|last1=Good|first1=Norman E.|last2=Winget|first2=G. Douglas|last3=Winter|first3=Wilhelmina|last4=Connolly|first4=Thomas N.|last5=Izawa|first5=Seikichi|last6=Singh|first6=Raizada M. M.|journal=Biochemistry|volume=5|pages=467–77|pmid=5942950|issue=2}}</ref> Its chemical structure contains a ] ring. ] is a similar ] buffering compound that contains a ] ring. With a ] of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH. '''MOPS''' ('''3-(''N''-morpholino)propanesulfonic acid''') is a ] introduced in the 1960s, one of the twenty ]. It is a structural analog to ],<ref>{{cite journal|doi=10.1021/bi00866a011|title=Hydrogen Ion Buffers for Biological Research|year=1966|last1=Good|first1=Norman E.|last2=Winget|first2=G. Douglas|last3=Winter|first3=Wilhelmina|last4=Connolly|first4=Thomas N.|last5=Izawa|first5=Seikichi|last6=Singh|first6=Raizada M. M.|journal=Biochemistry|volume=5|pages=467–77|pmid=5942950|issue=2}}</ref> and like MES, its structure contains a ] ring. ] is a similar ] buffering compound that contains a ] ring. With a ] of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.


==Applications== ==Applications==
MOPS is frequently used as a ] in ] and ]. It has been tested and recommended for ].<ref>{{cite journal|doi=10.1016/0003-2697(81)90178-0|pmid=6278979|title=A new discontinuous buffer system for the electrophoresis of cationic proteins at near-neutral pH|first2=ME|year=1981|last2=Hodes|last1=Thomas|first1=J|journal=Analytical Biochemistry|volume=118|issue=1|pages=194–6}}</ref> Usage above 20 mM in mammalian ] work is not recommended.<ref>{{cite journal|doi=10.1126/science.174.4008.500|pmid=5110427|title=Buffer Combinations for Mammalian Cell Culture|year=1971|last1=Eagle|first1=H.|journal=Science|volume=174|issue=4008|pages=500–3}}</ref> MOPS is frequently used as a ] in ] and ]. It has been tested and recommended for ].<ref>{{cite journal|doi=10.1016/0003-2697(81)90178-0|pmid=6278979|title=A new discontinuous buffer system for the electrophoresis of cationic proteins at near-neutral pH|first2=ME|year=1981|last2=Hodes|last1=Thomas|first1=J|journal=Analytical Biochemistry|volume=118|issue=1|pages=194–6}}</ref> Usage above 20 mM in mammalian ] work is not recommended.<ref>{{cite journal|doi=10.1126/science.174.4008.500|pmid=5110427|title=Buffer Combinations for Mammalian Cell Culture|year=1971|last1=Eagle|first1=H.|journal=Science|volume=174|issue=4008|pages=500–3|bibcode=1971Sci...174..500E|s2cid=29876583}}</ref> MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.<ref>{{cite web |url=https://bostonbioproducts.com/products/mops-buffer-1-m-ph-74-bbm-74 |title=Boston BioProducts - MOPS Buffer (1 M, pH 7.4)}}</ref>


==See also== ==See also==
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==References== ==References==
{{reflist|2}} {{reflist}}


==External links== ==External links==

*
* - Useful tool to calculate weight, volume, or concentration from molecular weight. * - Useful tool to calculate weight, volume, or concentration from molecular weight.
* *


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