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{{chembox |
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{{chembox |
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| Watchedfields = changed |
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| verifiedrevid = 400106502 |
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| verifiedrevid = 415851554 |
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| Name = Morin |
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| ImageFile = Morin.svg |
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| Name = Morin |
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| ImageFile = Morin.svg |
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| ImageSize = 250px |
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| ImageSize = 200px |
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| ImageAlt = Skeletal formula of morin |
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| ImageName = Morin structure |
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| ImageFile1 = Morin-3D-balls.png |
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| IUPACName = 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one |
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| ImageAlt1 = Ball-and-stick model of the morin molecule |
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| OtherNames= Aurantica<br>Al-Morin<br>Morin hydrate<br>Calico Yellow<br>''Toxylon pomiferum''<br>Bois d'arc<br>Osage orange extract |
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| IUPACName = 2′,3,4′,5,7-Pentahydroxyflavone |
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| Section1 = {{Chembox Identifiers |
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| SystematicName = 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4''H''-1-benzopyran-4-one |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| OtherNames = Aurantica<br>Al-Morin<br>Morin hydrate<br>Calico Yellow<br>''Toxylon pomiferum''<br>Bois d'arc<br>Osage orange extract |
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|Section1={{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 4444989 |
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| ChemSpiderID = 4444989 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = C10105 |
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| KEGG = C10105 |
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| InChI = 1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H |
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| InChI = 1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H |
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| InChIKey = YXOLAZRVSSWPPT-UHFFFAOYAH |
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| InChIKey = YXOLAZRVSSWPPT-UHFFFAOYAH |
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| ChEBI = 75092 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 28626 |
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| ChEMBL = 28626 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = YXOLAZRVSSWPPT-UHFFFAOYSA-N |
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| StdInChIKey = YXOLAZRVSSWPPT-UHFFFAOYSA-N |
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| CASNo = 654055-01-3 |
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| CASNo = 654055-01-3 |
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| PubChem = 5281670 |
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| PubChem = 5281670 |
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| IUPHAR_ligand = 411 |
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| IUPHAR_ligand = 411 |
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| SMILES = O=C1c3c(O/C(=C1/O)c2ccc(O)cc2O)cc(O)cc3O |
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| SMILES = O=C1c3c(O/C(=C1/O)c2ccc(O)cc2O)cc(O)cc3O |
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| Section2 = {{Chembox Properties |
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|Section2={{Chembox Properties |
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| C=15 |
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| Formula = C<sub>15</sub>H<sub>10</sub>O<sub>7</sub> |
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| H=10 |
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| MolarMass = 302.2357 g/mol |
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| O=7 |
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| ExactMass = 302.042653 |
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| Density = |
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| Density = 1.799 g/mL |
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| MeltingPt = <!-- °C --> |
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'''Morin''' is a chemical compound. It is a yellow color substance that can be isolated from '']'' (Osage orange), '']'' (old fustic) and from leaves of '']'' (common guava)<ref name="Psidium"></ref>. |
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'''Morin''' is a yellow chemical compound that can be isolated from '']'' (Osage orange), '']'' (old fustic), and from leaves of '']'' (common guava).<ref name="Psidium">{{cite journal | doi = 10.1016/j.fitote.2007.03.015 | title = Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens | journal = Fitoterapia | volume = 78 | issue = 6 | pages = 434–436 | year = 2007 | last1 = Rattanachaikunsopon | first1 = Pongsak | last2 = Phumkhachorn | first2 = Parichat | pmid = 17553634 }}</ref> In a preclinical '']'' study, morin was found to be a weak inhibitor of ] with an ] of 2.33 μM.<ref>{{cite journal | doi = 10.2174/092986706776361012 | title = Inhibition of Fatty Acid Synthase by Polyphenols | journal = Current Medicinal Chemistry | volume = 13 | issue = 8 | pages = 967–977 | year = 2006 | last1 = Tian | first1 = Wei-Xi | pmid = 16611078 }}</ref> Morin was also found to inhibit ] formation by ] (or amylin) and disaggregate amyloid fibers.<ref name="Noor2012">{{cite journal | doi = 10.1002/pro.2023| pmc = 3375438| title = Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers| journal = Protein Science| volume = 21| issue = 3| pages = 373–382| year = 2012| last1 = Noor| first1 = Harris| last2 = Cao| first2 = Ping| last3 = Raleigh| first3 = Daniel P.| pmid = 22238175}}</ref> |
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Morin can be used to test for the presence of ] or ] in a solution, since it forms characteristically ] ]es with them. |
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Morin can be used to test for the presence of ] or ] in a solution, since it forms characteristically ] ]es with them under UV light. |
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==]s== |
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== Glycosides == |
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* Morin-3-O-]<ref name="Psidium"></ref> |
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* Morin-3-O-]<ref name="Psidium" /> |
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* Morin-3-O-]<ref name="Psidium"/> |
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* Morin-3-O-]<ref name="Psidium"/> |
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==References== |
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== References == |
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<references/> |
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{{Reflist}} |
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{{Reflist}} |
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{{flavonol}} |
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{{flavonol}} |
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] |
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] |
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] |
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{{Polyphenol-stub}} |
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{{phenol-stub}} |
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] |
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] |
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] |
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