| Revision as of 13:13, 5 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{drugbox}} taken from revid 456839402 of page Pipecuronium_bromide for the Chem/Drugbox validation project (updated: 'UNII', 'ChEMBL', 'CAS_number'). |
Latest revision as of 06:58, 17 July 2024 edit Citation bot (talk | contribs)Bots5,418,263 edits Add: isbn, pmid. | Use this bot. Report bugs. | Suggested by Whoop whoop pull up | Category:Bromides | #UCB_Category 140/180 |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{cs1 config|name-list-style=vanc|display-authors=6}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| Verifiedfields = changed |
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⚫ |
| verifiedrevid = 464207336 |
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| Watchedfields = changed |
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| ⚫ |
| verifiedrevid = 400853810 |
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| IUPAC_name = (2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide |
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| IUPAC_name = (2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide |
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| image = Pipecuronium bromide.svg |
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| image = Pipecuronium bromide.svg |
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| width = 250 |
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| width = 250 |
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| image2 = Pipecuronium bromide ball-and-stick.png |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = |
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| tradename = Arduan |
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| Drugs.com = {{drugs.com|international|pipecuronium-bromide}} |
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| Drugs.com = {{drugs.com|international|pipecuronium-bromide}} |
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| pregnancy_category = |
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| pregnancy_category = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number_Ref = {{cascite|changed|??}} |
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| CAS_number = <!-- blanked - oldvalue: 52212-02-9 --> |
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| CAS_number = 52212-02-9 |
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| CAS_supplemental = {{CAS|68399-58-6}} |
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| CAS_supplemental = {{CAS|68399-58-6}} |
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| ATC_prefix = M03 |
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| ATC_prefix = M03 |
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| ChemSpiderID = 58815 |
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| ChemSpiderID = 58815 |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| UNII = <!-- blanked - oldvalue: R6ZTY81RE1 --> |
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| UNII = R6ZTY81RE1 |
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| KEGG_Ref = {{keggcite|changed|kegg}} |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D00764 |
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| KEGG = D00764 |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| ChEMBL = <!-- blanked - oldvalue: 1200722 --> |
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| ChEMBL = 1200722 |
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<!--Chemical data--> |
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| C=35 | H=62 | Br=2 | N=4 | O=4 |
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| C=35 | H=62 | Br=2 | N=4 | O=4 |
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| molecular_weight = 762.699 g/mol |
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| smiles = ..O=C(O6(N1CC(C)(C)CC1)C56(C)CC35CC4C(OC(=O)C)(N2CC(CC2)(C)C)C34C)C |
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| smiles = ..O=C(O6(N1CC(C)(C)CC1)C56(C)CC35CC4C(OC(=O)C)(N2CC(CC2)(C)C)C34C)C |
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| InChI = 1/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 |
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| InChIKey = TXWBOBJCRVVBJF-VGKUAFPFBT |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 |
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| StdInChI = 1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 |
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| StdInChIKey = TXWBOBJCRVVBJF-YTGGZNJNSA-L |
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| StdInChIKey = TXWBOBJCRVVBJF-YTGGZNJNSA-L |
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}} |
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}} |
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'''Pipecuronium''' ('''Arduan''') is a bisquaternary ] ]<ref>{{cite web|url=https://www.whocc.no/atc_ddd_index/?code=M03AC06 | title = Pipecuronium Bromide | id = M03AC06 | work = WHOCC - ATC/DDD Index}}</ref> which blocks ]<ref name="drugbank1">{{cite web|url=https://www.drugbank.ca/drugs/DB01338|title = Pipecuronium | work = DrugBank }}</ref><ref>{{cite book | vauthors = Singh H, Jindal DP, Yadav MR, Kumar M | chapter = 5 Heterosteroids and drug research. | title = Progress in Medicinal Chemistry | date = January 1991 | volume = 28 | pages = 233-300 (270) | doi = 10.1016/S0079-6468(08)70366-7 | pmid = 1843548 | isbn = 978-0-444-81275-9 }}</ref> at the ]. It is also an antagonist of ] and ]<ref name="drugbank1"/> and is the most ] ] of the aminosteroid class.{{citation needed|date=April 2019}} |
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It is sold under the ] Arduan and Pycuron.<ref>{{cite web|url=https://www.drugs.com/international/pipecuronium-bromide.html |title=Pipecuronium - brand name list from |publisher=Drugs.com |date= |accessdate=2022-09-17}}</ref> |
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==See also== |
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*] |
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== References == |
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{{reflist}} |
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{{Muscle relaxants}} |
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{{Nicotinic acetylcholine receptor modulators}} |
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] |
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] |
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{{steroid-stub}} |
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{{musculoskeletal-drug-stub}} |