| Revision as of 13:26, 5 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 460509929 of page Pleuran for the Chem/Drugbox validation project (updated: 'CASNo'). |
Latest revision as of 02:37, 28 April 2024 edit Goodmans238 (talk | contribs)Extended confirmed users1,266 edits Rescuing 1 sources and tagging 0 as dead.) #IABot (v2.0.9.5Tag: IABotManagementConsole [1.3] |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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| ImageFile = Beta-1,3-1,6-glucan.png |
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| CASNo = <!-- blanked - oldvalue: 159940-37-1 --> |
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| CASNo = 159940-37-1 |
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| Formula = (C<sub>6</sub>H<sub>10</sub>O<sub>5</sub>)<sub>x</sub> |
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| Formula = (C<sub>6</sub>H<sub>10</sub>O<sub>5</sub>)<sub>x</sub> |
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'''Pleuran''' is an insoluble ] (]), isolated from '']''.<ref>{{cite journal |vauthors=Karácsonyi S, Kuniak L | year = 1994 | title = Polysaccharides of ''Pleurotus ostreatus'': Isolation and structure of pleuran, an alkali-insoluble β-glucan | journal = Carbohydrate Polymers | volume = 24 | issue = 2 | pages = 107–111 | publisher = ] | doi = 10.1016/0144-8617(94)90019-1 }}</ref> |
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Pleuran belongs to a group of ] ] commonly called ]s demonstrating ] properties. These immunomodulating properties render the host more resistant to infections and ]s.<ref>{{cite journal | last = Di Luzio | first = NR | year = 1985 | title = Update on the immunomodulating activities of glucans | journal = Springer Seminars in Immunopathology | volume = 8 | issue = 4 | pages = 387–400 | publisher = ] | location = Germany | pmid = 4089757 | doi = 10.1007/BF01857392 | s2cid = 24803241 | doi-access = free }}</ref> |
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In a study published in December 2010, pleuran demonstrated to have a protective effect against exercise-induced suppression of ] activity (]) in subjects taking 100 mg per day.<ref>{{cite journal|last=Bobovčák|first=M|author2=Kuniaková, R, Gabriž, J, Majtán, J|title=Effect of Pleuran (β-glucan from Pleurotus ostreatus) supplementation on cellular immune response after intensive exercise in elite athletes.|journal=Applied Physiology, Nutrition, and Metabolism|date=December 2010|volume=35|issue=6|pages=755–62|pmid=21164546|doi=10.1139/h10-070}}</ref> |
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In another study published in 2011, pleuran reduced the incidence of ] and increased the number of circulating NK cells.<ref>{{cite journal|last=Bergendiova|first=K|author2=Tibenska, E, Majtan, J|title=Pleuran (β-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes.|journal=European Journal of Applied Physiology|date=2011-01-20|pmid=21249381|doi=10.1007/s00421-011-1837-z|volume=111|issue=9|pages=2033–40|s2cid=25411018}}</ref> |
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Pleuran is also being studied as a potential ].<ref>{{cite journal | vauthors = Vogel FR, Powell MF, Alving CR | title = A Compendium of Vaccine Adjuvants and Excipients | journal = Pharmaceutical Biotechnology | version = 2nd ed | pages = 141–228 | publisher = ] | year = 1998 | volume = 6 | doi = 10.1007/978-1-4615-1823-5_7 | pmid = 7551218 | isbn = 978-1-4613-5737-7 | url = http://www.niaid.nih.gov/hivvaccines/pdf/compendium.pdf | accessdate = 2008-05-08 | archive-date = 2007-07-15 | archive-url = https://web.archive.org/web/20070715043825/http://www.niaid.nih.gov/hivvaccines/pdf/compendium.pdf | url-status = live }}</ref> |
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==References== |
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{{reflist}} |
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] |
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{{biochem-stub}} |