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Revision as of 13:54, 5 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{drugbox}} taken from revid 447933611 of page Potassium_gluconate for the Chem/Drugbox validation project (updated: 'CAS_number').  Latest revision as of 18:28, 16 December 2024 edit Maxim Masiutin (talk | contribs)Extended confirmed users, IP block exemptions, Pending changes reviewers31,042 editsm added clarification 
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{{Short description|Chemical compound}}
{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}}
{{Drugbox {{Drugbox
| Verifiedfields = changed
| Watchedfields = changed | Watchedfields = changed
| verifiedrevid = 400858247 | verifiedrevid = 464211745
| drug_name =
⚫ | IUPAC_name = potassium (2''R'',3''S'',4''R'',5''R'')-2,3,4,5,6-pentahydroxyhexanoate
| type =
⚫ | IUPAC_name = Potassium (2''R'',3''S'',4''R'',5''R'')-2,3,4,5,6-pentahydroxyhexanoate
| image = Potassium gluconate.svg | image = Potassium gluconate.svg
⚫ <!--Clinical data-->| alt =

| caption =
⚫ <!--Clinical data-->
| image2 = Potassium-gluconate-3D-balls-ionic.png
| tradename = | tradename =
| Drugs.com = {{drugs.com|CDI|potassium_gluconate}} | Drugs.com = {{drugs.com|CDI|potassium_gluconate}}
| MedlinePlus = a601072 | MedlinePlus = a601072
| licence_EU =
| licence_US =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X --> | pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category =
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
⚫ <!--Identifiers-->| legal_status =

| CAS_number_Ref = {{cascite|changed|??}}
⚫ <!--Identifiers-->
| CAS_number = <!-- blanked - oldvalue: 299-27-4 --> | CAS_number = 299-27-4
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 12H3K5QKN9
| ATC_prefix = A12 | ATC_prefix = A12
| ATC_suffix = BA05 | ATC_suffix = BA05
| PubChem = 9288 | PubChem = 16760467
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| DrugBank =
| ChemSpiderID = 8931 | ChemSpiderID = 8931
⚫ <!--Chemical data-->| C = 6

| H = 11
⚫ <!--Chemical data-->
| C=6 | H=11 | K=1 | O=7 | K = 1
| O = 7
| molecular_weight = 234.246 g/mol
| smiles = .C(=O)(O)(O)(O)(O)CO | smiles = .C(=O)(O)(O)(O)(O)CO
| InChI = 1/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
| InChIKey = HLCFGWHYROZGBI-PJANJZMKBO
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1 | StdInChI = 1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = HLCFGWHYROZGBI-JJKGCWMISA-M | StdInChIKey = HLCFGWHYROZGBI-JJKGCWMISA-M
| melting_point = 180
| melting_notes = (decomposes)
| solubility =
}} }}
'''Potassium gluconate''' is the ] ] of the ] of ]. It is also referred to as 2,3,4,5,6-pentahydroxycaproic acid potassium salt, <small>D</small>-gluconic acid potassium salt, or potassium <small>D</small>-gluconate.<ref>{{cite web|url=http://www.sigmaaldrich.com/catalog/search?interface=Product%20Name&term=potassium+gluconate |title=Product Name potassium gluconate |publisher=] |date= |accessdate=2013-03-09}}</ref>

It contains 16.69% <!-- =100*39.0983/234.246 --> elemental potassium by mass. Thus 5.99 g <!-- =100/16.6911 --> of potassium gluconate contains 1 g of potassium.

It has a density of 1.73 g/cm<sup>3</sup>.<ref>{{cite web|url=http://www.wolframalpha.com/input/?i=potassium+gluconate |title=Potassium gluconate |publisher=] |date= |accessdate=2013-04-21}}</ref>

==Dietary uses==
Potassium gluconate is used as a ] and ]. It is sold over-the-counter as tablets or capsules providing up to 593 mg of potassium gluconate, thereby containing 99 mg <!-- =16.691% --> or 2.53 ] of elemental potassium. This is the permissible upper limit for each tablet or capsule of over-the-counter potassium supplements sold in the US. Potassium gluconate is also sold over-the-counter as bulk powder.

As a ], potassium gluconate is used as an ] and ] food.<ref>{{cite web |url=http://www.fao.org/fileadmin/user_upload/jecfa_additives/docs/Monograph1/Additive-337.pdf |title=Potassium Gluconate |author=] |date= |website= |publisher= |access-date=28 November 2018}}</ref><ref>{{cite web |url=http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=4660 |title=Potassium Gluconate |author=Joint FAO/WHO Expert Committee on Food Additives |date= |website=Evaluations of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) |publisher=] |access-date=28 November 2018}}</ref> It is known as ] reference '''E577'''.

===Safety===
Its oral ] (LD<sub>50</sub>) in rats is 10.38 g/kg.<ref>{{cite web|url=http://www.sigmaaldrich.com/MSDS/MSDS/DisplayMSDSPage.do?country=US&language=en&productNumber=P1847&brand=SIAL&PageToGoToURL=http%3A%2F%2Fwww.sigmaaldrich.com%2Fcatalog%2Fsearch%3Finterface%3DProduct%2520Name%26term%3DPotassium%2Bgluconate%26lang%3Den%26region%3DUS%26focus%3Dproduct%26N%3D220003048%2B219853269%2B219853286%26mode%3Dmode%2520matchpartialmax |title=MSDS - P1847 |publisher=] |date= |accessdate=2013-04-21}}</ref> This is not an indicator of a safe oral daily dose in rats or humans.

==References==
{{Reflist}}

==External links==
* from ]
* on ]

{{Mineral supplements}}

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