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Revision as of 02:30, 22 September 2011 editEmausBot (talk | contribs)Bots, Template editors2,856,891 editsm r2.6.4) (Robot: Modifying ar:بولولان← Previous edit Latest revision as of 05:10, 16 October 2024 edit undoCrafterNova (talk | contribs)Extended confirmed users16,639 edits all polysaccharides are polymers by definition. it is redundant to say "polysaccharide polymer"Tags: Mobile edit Mobile web edit Advanced mobile edit 
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{{chembox {{chembox
| Verifiedfields = changed
| verifiedrevid = 444074656
| Watchedfields = changed
| verifiedrevid = 451781241
| ImageFile = Pullulan.png | ImageFile = Pullulan.png
| ImageSize = | ImageSize =
| IUPACName = | IUPACName =
| OtherNames = E1204 | OtherNames = E1204
| Section1 = {{Chembox Identifiers |Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 9057-02-7 | CASNo = 9057-02-7
| EINECS = 232-945-1 | EINECS = 232-945-1
| PubChem = | PubChem =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = none
| UNII_Ref = {{fdacite|correct|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 8ZQ0AYU1TT | UNII = 8ZQ0AYU1TT
| SMILES = }} | SMILES = }}
| Section2 = {{Chembox Properties |Section2={{Chembox Properties
| Formula = (C<sub>6</sub>H<sub>12</sub>O<sub>5</sub>)<sub>n</sub> | Formula = (C<sub>6</sub>H<sub>10</sub>O<sub>5</sub>)<sub>n</sub>
| MolarMass = | MolarMass =
| Appearance = White powder | Appearance = White powder
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| BoilingPt = | BoilingPt =
| Solubility = Soluble}} | Solubility = Soluble}}
| Section3 = {{Chembox Hazards |Section3={{Chembox Hazards
| MainHazards = | MainHazards =
| FlashPt = | FlashPt =
| Autoignition = }} | AutoignitionPt = }}
}} }}


'''Pullulan''' is a ] ] consisting of ] units, also known as α-1,4- ;α-1,6-]'. Three ] units in maltotriose are connected by an α-1,4 ], whereas consecutive maltotriose units are connected to each other by an α-1,6 ]. Pullulan is produced from ] by the ] '']''. '''Pullulan''' is a ] consisting of ] units, also known as α-1,4- ;α-1,6-]'. Three ] units in maltotriose are connected by an α-1,4 ], whereas consecutive maltotriose units are connected to each other by an α-1,6 ]. Pullulan is produced from ] by the ] '']''. Pullulan is mainly used by the cell to resist ] and ]. The presence of this polysaccharide also facilitates diffusion of molecules both into and out of the cell.<ref name=Rehm>{{cite book |author=Rehm B.H.A |year=2009 |title=Microbial production of biopolymers and polymers precursors |page=230 |publisher=Caister Academic Press }}</ref>
As an edible, mostly tasteless polymer, the chief commercial use of pullulan is in the manufacture of edible films that are used in various breath freshener or ] products such as ] Cool Mint of Johnson and Johnson (USA) and Meltz Super Thin Mints of Avery Bio-Tech Private Ltd. (India). Pullulan and ] can also be used as a ] substitute for drug capsules, rather than gelatine. As a ], it is known by the ] E1204.


Pullulan has also be explored as natural polymeric ] to fabricated ] scaffold for ] ],<ref>{{Cite journal |last1=Fricain |first1=Jean Christophe |last2=Schlaubitz |first2=Silke |last3=Le Visage |first3=Catherine |last4=Arnault |first4=Isabelle |last5=Derkaoui |first5=Sidi Mohammed |last6=Siadous |first6=Robin |last7=Catros |first7=Sylvain |last8=Lalande |first8=Charlotte |last9=Bareille |first9=Reine |last10=Renard |first10=Martine |last11=Fabre |first11=Thierry |last12=Cornet |first12=Sandro |last13=Durand |first13=Marlène |last14=Léonard |first14=Alain |last15=Sahraoui |first15=Nouredine |date=2013-04-01 |title=A nano-hydroxyapatite – Pullulan/dextran polysaccharide composite macroporous material for bone tissue engineering |url=https://www.sciencedirect.com/science/article/pii/S014296121300077X |journal=Biomaterials |language=en |volume=34 |issue=12 |pages=2947–2959 |doi=10.1016/j.biomaterials.2013.01.049 |pmid=23375393 |issn=0142-9612}}</ref> ] tissue engineering,<ref>{{Cite journal |last1=Chen |first1=Feng |last2=Yu |first2=Songrui |last3=Liu |first3=Bing |last4=Ni |first4=Yunzhou |last5=Yu |first5=Chunyang |last6=Su |first6=Yue |last7=Zhu |first7=Xinyuan |last8=Yu |first8=Xiaowei |last9=Zhou |first9=Yongfeng |last10=Yan |first10=Deyue |date=2016-01-28 |title=An Injectable Enzymatically Crosslinked Carboxymethylated Pullulan/Chondroitin Sulfate Hydrogel for Cartilage Tissue Engineering |journal=Scientific Reports |language=en |volume=6 |issue=1 |pages=20014 |doi=10.1038/srep20014 |pmid=26817622 |issn=2045-2322|pmc=4730219 |bibcode=2016NatSR...620014C }}</ref> and ] regeneration.<ref>{{Cite journal |last1=Henry |first1=Nina |last2=Clouet |first2=Johann |last3=Fragale |first3=Audrey |last4=Griveau |first4=Louise |last5=Chédeville |first5=Claire |last6=Véziers |first6=Joëlle |last7=Weiss |first7=Pierre |last8=Le Bideau |first8=Jean |last9=Guicheux |first9=Jérôme |last10=Le Visage |first10=Catherine |date=2017-01-01 |title=Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine |journal=Drug Delivery |language=en |volume=24 |issue=1 |pages=999–1010 |doi=10.1080/10717544.2017.1340362 |issn=1071-7544 |pmc=8241148 |pmid=28645219}}</ref>
As an edible, mostly tasteless polymer, the chief commercial use of pullulan is in the manufacture of edible films that are used in various breath freshener or ] products such as ] Cool Mint. As a ], it is known by the ] E1204.


==See also== ==See also==
*] *]
*]


== References == == References ==
{{Reflist}}
* (abstract) * (abstract)
* *
* {{MeshName|pullulan}} * {{MeshName|pullulan}}
* *
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{{biotech-stub}} {{biotech-stub}}


== Further reading ==
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* Saman Zarei; Faramarz Khodaiyan; Seyed Saeid Hosseini; John F. Kennedy. (October 2020) . ''Applied Food Biotechnology'', Vol. 7 No. 4 (2020), 18 August 2020 , Page 263-272. https://doi.org/10.22037/afb.v7i4.29747
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