| Revision as of 13:43, 6 December 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,055 edits Saving copy of the {{chembox}} taken from revid 460123312 of page Satratoxin-H for the Chem/Drugbox validation project (updated: 'CASNo'). |
Latest revision as of 02:09, 18 August 2024 edit Mfernflower (talk | contribs)Extended confirmed users7,863 editsNo edit summaryTags: Mobile edit Mobile web edit Advanced mobile edit |
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{{MCN|date=April 2024}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{chembox |
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{{chembox |
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| Verifiedfields = changed |
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| verifiedrevid = 401048847 |
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| verifiedrevid = 464387474 |
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| ImageFile = Satratoxin-H.svg |
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| ImageFile = Satratoxin-H.svg |
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| ImageSize = 170px |
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| ImageSize = 170px |
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3,14(9H)-dione</small> |
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3,14(9H)-dione</small> |
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| OtherNames = |
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| OtherNames = |
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| Section1 = {{Chembox Identifiers |
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|Section1={{Chembox Identifiers |
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| InChI = 1/C29H36O9/c1-17-7-10-27-15-34-24(32)13-19-8-11-35-28(18(2)30,25(19)33)9-5-4-6-23(31)38-20-14-22(37-21(27)12-17)29(16-36-29)26(20,27)3/h4-6,9,12-13,18,20-22,25,30,33H,7-8,10-11,14-16H2,1-3H3/b6-4-,9-5+,19-13+/t18-,20+,21+,22+,25+,26+,27+,28+,29+/m0/s1 |
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| InChI = 1/C29H36O9/c1-17-7-10-27-15-34-24(32)13-19-8-11-35-28(18(2)30,25(19)33)9-5-4-6-23(31)38-20-14-22(37-21(27)12-17)29(16-36-29)26(20,27)3/h4-6,9,12-13,18,20-22,25,30,33H,7-8,10-11,14-16H2,1-3H3/b6-4-,9-5+,19-13+/t18-,20+,21+,22+,25+,26+,27+,28+,29+/m0/s1 |
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| InChIKey = MUACSCLQRGEGOE-PQGPUMQGBS |
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| InChIKey = MUACSCLQRGEGOE-PQGPUMQGBS |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = MUACSCLQRGEGOE-PQGPUMQGSA-N |
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| StdInChIKey = MUACSCLQRGEGOE-PQGPUMQGSA-N |
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| CASNo_Ref = {{cascite|changed|??}} |
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| CASNo = <!-- blanked - oldvalue: 53126-64-0 --> |
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| CASNo=53126-64-0 |
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| PubChem=6438478 |
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| PubChem=6438478 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID=16736977 |
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| ChemSpiderID=16736977 |
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| SMILES = C(O)12\C=C\C=C/C(=O)O4C6O3/C=C(/C)CC3(COC(=O)/C=C(\CCO1)2O)4(C)56CO5 |
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| SMILES = C(O)12\C=C\C=C/C(=O)O4C6O3/C=C(/C)CC3(COC(=O)/C=C(\CCO1)2O)4(C)56CO5 |
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}} |
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}} |
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| Section2= {{Chembox Properties |
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|Section2={{Chembox Properties |
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| Formula=C<sub>29</sub>H<sub>36</sub>O<sub>9</sub> |
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| Formula=C<sub>29</sub>H<sub>36</sub>O<sub>9</sub> |
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| MolarMass=528.591 |
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| MolarMass=528.591 |
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| MeltingPt= |
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| Solubility=}} |
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| Solubility=insoluble}} |
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| Section3= {{Chembox Hazards |
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|Section3={{Chembox Hazards |
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| GHSPictograms = {{GHS skull and crossbones}} |
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| MainHazards= |
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| MainHazards = Highly toxic}} |
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| FlashPt= |
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| Autoignition=}} |
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}} |
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}} |
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'''Satratoxin-H''', a ] ], is a naturally occurring toxin produced by the ]s '']'' and '']'' which is highly toxic to humans and animals. The clinical condition it causes is known as ''Stachybotrotoxicosis''. It is related to the mycotoxin ], but unlike T-2 has not been reported to have been used as a ]. |
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== Properties == |
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Satratoxin-H is almost completely insoluble in water, but is easily soluble in lower alcohols and polar solvents such as ], ], ], ] and ].<ref> {{webarchive|url=https://web.archive.org/web/20070505162235/http://www.cbwinfo.com/Biological/Toxins/Satra.html |date=2007-05-05 }}</ref> |
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Satratoxin-H is not officially classified as a ]. {{citation needed|date=April 2017}} |
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== Effects == |
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Satratoxin-H is extremely versatile. Contact with the solution through ingestion, inhalation, or even prolonged physical contact produces symptoms similar to those listed below. |
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* a rash that becomes a moist dermatitis |
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* ]s |
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* chest pain |
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* ] (bleeding in the lungs) |
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* fever |
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* headache |
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* fatigue |
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However, if consumed in large quantities, it can be lethal. Satratoxin-H has little effect on bare skin, and does not blister it in the way many chemical weapons do. However, upon contact with sensitive surfaces (eyes, interior of mouth or nose), inflammation will occur. |
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Satratoxin-H has an {{LD50}} for mice of 1.0-1.4 mg/kg, upon injection. Otherwise it is reported to be about five times as toxic as T-2.<ref></ref> |
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== References == |
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{{reflist}} |
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* {{ cite journal |author1=Croft, W. A. |author2=Jarvis, B. B. |author3=Yatawara, C. S. | title = Airborne outbreak of trichothecene toxicosis | journal = Atmospheric Environment | year = 1986 | volume = 20 | issue = 3 | pages = 549–552 | doi = 10.1016/0004-6981(86)90096-X |bibcode=1986AtmEn..20..549C }} |
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* {{ cite journal |author1=Nikulin, M. |author2=Reijula, K. |author3=Jarvis, B. B. |author4=Veijalainen, P. |author5=Hintikka, E. L. | title = Effects of Intranasal Exposure to Spores of ''Stachybotrys atra'' in Mice | journal = Fundamental and Applied Toxicology | year = 1997 | volume = 35 | issue = 2 | pages = 182–188 | pmid = 9038239 | doi=10.1093/toxsci/35.2.182| doi-access = free }} |
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] |