| Revision as of 12:46, 15 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{chembox}} taken from revid 473082645 of page Zinc_acetate for the Chem/Drugbox validation project (updated: 'ChEMBL'). |
Latest revision as of 21:04, 27 June 2024 edit ArticCynda (talk | contribs)Extended confirmed users553 edits →UsesTag: 2017 wikitext editor |
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{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}} |
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{{chembox |
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{{chembox |
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| verifiedrevid = 470635915 |
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| verifiedrevid = 476996264 |
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| ImageName = Zinc acetate |
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| ImageFile2 = Zinc acetate.JPG |
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| ImageName = Zinc acetate |
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| ImageFile1 = Zinc acetate.JPG |
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| ImageSize2= 200px |
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| ImageSize2 = |
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| ImageName2 = Zinc acetate crystals |
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| IUPACName = Zinc acetate |
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| ImageName1 = Zinc acetate crystals |
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| ImageFile2 = ZNAQAC04.png |
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| OtherNames = Acetic acid, Zinc salt<br />Acetic acid, Zinc(II) salt<br />Dicarbomethoxyzinc<br />Zinc diacetate |
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| IUPACName = Zinc acetate |
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| Section1 = {{Chembox Identifiers |
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| OtherNames = Acetic acid, Zinc salt<br />Acetic acid, Zinc(II) salt<br />Dicarbomethoxyzinc<br />Zinc diacetate |
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| SMILES = .C(=O)C.C(=O)C |
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|Section1={{Chembox Identifiers |
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| CASNo = 557-34-6 |
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| CASNo_Comment =(anhydrous) |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo2_Ref = {{cascite|correct|CAS}} |
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| CASNo2 = 5970-45-6 |
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| CASNo2_Comment =(dihydrate) |
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| ChEBI = 62984 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 10719 |
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| ChemSpiderID = 10719 |
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| EC_number = 209-170-2 |
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| PubChem = 11192 |
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| PubChem = 11192 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 1200928 |
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| RTECS = ZG8750000 |
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| UNNumber = 3077 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = H2ZEY72PME |
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| UNII = H2ZEY72PME |
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| UNII_Comment = (anhydrous) |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| UNII2_Ref = {{fdacite|correct|FDA}} |
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| ChEMBL = <!-- blanked - oldvalue: 1200928 --> |
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| UNII2 = FM5526K07A |
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| UNII2_Comment = (dihydrate) |
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| InChI = 1/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2 |
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| InChI = 1/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2 |
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| InChIKey = DJWUNCQRNNEAKC-NUQVWONBAP |
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| InChIKey = DJWUNCQRNNEAKC-NUQVWONBAP |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = DJWUNCQRNNEAKC-UHFFFAOYSA-L |
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| StdInChIKey = DJWUNCQRNNEAKC-UHFFFAOYSA-L |
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| SMILES = .C(=O)C.C(=O)C |
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| CASNo = 557-34-6 |
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| SMILES1 = C/C1=/\35O/C(C)=\\26\=C(C)/O4(O1)/=C(C)\O(=/C(C)=2)(O/C(C)=3)456 |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| SMILES1_Comment = basic zinc acetate |
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| CASOther = {{CAS|5970-45-6}} |
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}} |
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| RTECS = ZG8750000 |
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|Section2={{Chembox Properties |
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| Formula = Zn(CH<sub>3</sub>COO)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub> (dihydrate) |
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| MolarMass = 219.50 g/mol (dihydrate)<br />183.48 g/mol (anhydrous) |
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| Appearance = White solid (all forms) |
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| Density = 1.735 g/cm<sup>3</sup> (dihydrate) |
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| Solubility = 43 g/100 mL (20 °C, dihydrate) |
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| SolubleOther = 1.5 g/100 mL (methanol) |
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| MeltingPt= Decomposes at |
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| MeltingPtC = 237 |
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| MeltingPt_notes = (dihydrate loses water at 100 °C) |
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| BoilingPt = decomposes |
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| MagSus = −101.0·10<sup>−6</sup> cm<sup>3</sup>/mol (+2 H<sub>2</sub>O) |
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}} |
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|Section3={{Chembox Structure |
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| MolShape = tetrahedral |
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| Coordination = octahedral (dihydrate) |
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| CrystalStruct = }} |
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|Section6={{Chembox Pharmacology |
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| ATCCode_prefix = A16 |
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| ATCCode_prefix = A16 |
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| ATCCode_suffix = AX05 |
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| ATCCode_suffix = AX05 |
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}} |
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|Section7={{Chembox Hazards |
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| ExternalSDS = |
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| MainHazards = |
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| GHSPictograms = {{GHS05}}{{GHS07}}{{GHS09}} |
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| GHSSignalWord = Danger |
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| HPhrases = {{H-phrases|302|318|319|410|411}} |
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| PPhrases = {{P-phrases|264|270|273|280|301+312|305+351+338|310|330|337+313|391|501}} |
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}} |
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}} |
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| Section2 = {{Chembox Properties |
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|Section8={{Chembox Related |
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| OtherAnions = ] |
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| Formula = C<sub>4</sub>H<sub>10</sub>O<sub>6</sub>Zn (dihydrate) |
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| OtherCations = ] |
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| MolarMass = 219.50 g/mol (dihydrate)<br />183.48 g/mol (anhydrous) |
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| OtherCompounds = ]}} |
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| Appearance = White solid (all forms) |
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}} |
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| Density = 1.735 g/cm<sup>3</sup> (dihydrate) |
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| Solubility = 43 g/100 mL (20 °C, dihydrate) |
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'''Zinc acetate''' is a ] with the ] Zn(CH<sub>3</sub>CO<sub>2</sub>)<sub>2</sub>, which commonly occurs as the ] Zn(CH<sub>3</sub>CO<sub>2</sub>)<sub>2</sub>·2H<sub>2</sub>O. Both the hydrate and the ] forms are colorless solids that are used as dietary supplements. When used as a ], it has the ] E650. |
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| SolubleOther = soluble in ] |
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| MeltingPt = Decomposes 237 °C <br />(dihydrate loses water at 100 °C) |
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==Uses== |
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| BoilingPt = decomp. |
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Zinc acetate is a component of some medicines, e.g., ].<ref>{{cite web |title=Zinc – Fact Sheet for Health Professionals |url=https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional|publisher=Office of Dietary Supplements, US National Institutes of Health |date=February 11, 2016|access-date=November 15, 2018}}</ref> Zinc acetate can also be used as a dietary supplement.<ref>{{cite journal | doi = 10.3945/jn.113.181487| pmid = 24259556| pmc = 3901420| title = Zinc Absorption by Young Adults from Supplemental Zinc Citrate is Comparable with That from Zinc Gluconate and Higher than from Zinc Oxide| journal = The Journal of Nutrition| volume = 144| issue = 2| pages = 132–136| year = 2014| last1 = Wegmüller| first1 = Rita| last2 = Tay| first2 = Fabian| last3 = Zeder| first3 = Christophe| last4 = Brnić| first4 = Marica| last5 = Hurrell| first5 = Richard F.}}</ref> As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for ].<ref>{{cite web | access-date= November 15, 2018 | title = Wilson Disease | url = https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/wilson-disease/Pages/facts.aspx | website=NIDDK | date=July 2014 |url-status = live | archive-url = https://web.archive.org/web/20161004223012/https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/wilson-disease/Pages/facts.aspx | archive-date=2016-10-04}}</ref> Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion, or combined with an antibiotic such as ] for the topical treatment of acne.<ref>{{cite journal | pmid = 2138176| year = 1990| last1 = Schachner| first1 = L.| title = Topical erythromycin and zinc therapy for acne| journal = Journal of the American Academy of Dermatology| volume = 22| issue = 2 Pt 1| pages = 253–60| last2 = Eaglstein| first2 = W.| last3 = Kittles| first3 = C.| last4 = Mertz| first4 = P.| doi = 10.1016/0190-9622(90)70034-f| doi-access = free}}</ref> It is commonly sold as a topical anti-itch ointment. |
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}} |
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| Section3 = {{Chembox Structure |
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Zinc acetate is used as the catalyst for the industrial production of ] from ]: |
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| MolShape = tetrahedral |
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{{chem2|1=CH3CO2H + C2H2 -> CH3CO2CH=CH2}}. Approximately 1/3 of the worlds production uses this route, which because of its environmental impact, is mainly practiced in countries with relaxed environmental regulations such as China.<ref>{{Ullmann|doi=10.1002/14356007.a27_419.pub2|title=Vinyl Esters |year=2019 |last1=Bienewald |first1=Frank |last2=Leibold |first2=Edgar |last3=Tužina |first3=Pavel |last4=Roscher |first4=Günter |pages=1–16 |isbn=978-3-527-30385-4 }}</ref> |
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| Coordination = octahedral (dihydrate) |
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| CrystalStruct = }} |
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==Preparation== |
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| Section7 = {{Chembox Hazards |
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Zinc acetates are prepared by the action of ] on ] or ] metal. Treatment of ] with ] is an alternative route.<ref>{{cite book|author1=O. F. Wagenknecht|author2=R. Juza|chapter=Zinc Acetate|title=Handbook of Preparative Inorganic Chemistry, 2nd Ed. |editor=G. Brauer|publisher=Academic Press|year=1963|place=NY, NY|volume=2pages=1087}}</ref> |
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| ExternalMSDS = |
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| MainHazards = mildly toxic |
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==Structures== |
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| RPhrases = {{R22}} {{R36}} {{R50/53}} |
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In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.<ref>{{cite journal|last1=Clegg|first1=W.|last2=Little|first2=I. R.|last3=Straughan|first3=B. P.|title=Monoclinic anhydrous zinc(II) acetate|journal=Acta Crystallographica Section C|date=15 December 1986|volume=42|issue=12|pages=1701–1703|doi=10.1107/S010827018609087X|doi-access=|bibcode=1986AcCrC..42.1701C }}</ref><ref>{{cite journal|last1=He|first1=Hongshan|title=A new monoclinic polymorph of anhydrous zinc acetate|journal=Acta Crystallographica Section E|date=15 November 2006|volume=62|issue=12|pages=m3291–m3292|doi=10.1107/S1600536806046678}}</ref><ref>{{cite journal |author1=Capilla, A. V. |author2=Aranda, R. A. | title = Anhydrous Zinc(II) Acetate (CH<sub>3</sub>-COO)<sub>2</sub>Zn | journal = Crystal Structure Communications | year = 1979 | volume = 8 | pages = 795–797}}</ref> |
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| SPhrases = {{S26}} {{S60}} {{S61}} |
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}} |
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In the dihydrate, zinc is octahedral, wherein both acetate groups are bidentate.<ref>{{cite journal|last1=van Niekerk|first1=J. N.|last2=Schoening|first2=F. R. L.|last3=Talbot|first3=J. H.|title=The crystal structure of zinc acetate dihydrate, Zn(CH<sub>3</sub>COO)<sub>2</sub>.2H<sub>2</sub>O|journal=Acta Crystallographica|date=10 September 1953|volume=6|issue=8|pages=720–723|doi=10.1107/S0365110X53002015|doi-access=free|bibcode=1953AcCry...6..720V }}</ref><ref>{{cite journal|last1=Ishioka|first1=T.|last2=Murata|first2=A.|last3=Kitagawa|first3=Y.|last4=Nakamura|first4=K. T.|title=Zinc(II) Acetate Dihydrate|journal=Acta Crystallographica Section C|date=15 August 1997|volume=53|issue=8|pages=1029–1031|doi=10.1107/S0108270197004484|bibcode=1997AcCrC..53.1029I }}</ref> |
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| Section8 = {{Chembox Related |
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| OtherAnions = ] |
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==Reactions== |
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| OtherCations = ] |
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Heating Zn(CH<sub>3</sub>CO<sub>2</sub>)<sub>2</sub> in a vacuum results in a loss of ], leaving a residue of "basic zinc acetate," with the formula Zn<sub>4</sub>O(CH<sub>3</sub>CO<sub>2</sub>)<sub>6</sub>. It can also be prepared by a reaction of glacial acetic acid with ].<ref>{{cite journal |last1=Poshkus |first1=Algirdas C. |title=Improved synthesis of basic zinc acetate, hexakis(.mu.-acetato)-.mu.-oxotetrazinc |journal=Industrial & Engineering Chemistry Product Research and Development |date=June 1983 |volume=22 |issue=2 |pages=380–381 |doi=10.1021/i300010a041}}</ref> The ] has a ] structure with an oxide ligand at its center<ref>{{cite journal |author1=Koyama, H. |author2=Saito, Y. | title = The Crystal Structure of Zinc Oxyacetate, Zn<sub>4</sub>O(CH<sub>3</sub>COO)<sub>6</sub> | journal = ] | year = 1954 | volume = 27 | pages = 112–114 | doi = 10.1246/bcsj.27.112 | issue = 2| doi-access = free }}</ref> Basic zinc acetate is a common precursor to ]s (MOFs). |
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| OtherCpds = ]}} |
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{{Gallery |mode=packed |align=center |height=200 |
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|File:BasicZnAcetate.png |
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==See also== |
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* ] - isostructural with basic zinc acetate |
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==References== |
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{{Reflist}} |
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{{Zinc compounds}} |
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{{Acetates}} |
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] |
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] |
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] |