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When appropriate, protection levels are automatically sensed, described and categorized.

Hemolysis assay

The hemolysis assay is a practical scalable assay for the initial assessment of cytotoxicity in drug development.

dinQ

dinQ, DNA-damage-inducible protein Q produces two major transcripts, only one, however, +44, is actively translated. Translation is initiated using the unusual GUG start codon and results in a 27 amino acid peptide. Plasmid-based expression of C-terminal triple FLAG-tagged dinQ located DinQ in the inner-membrane of E. coli. Overexpression of dinQ led to reduced survival, loss of transmembrane electrical polarity and reduced intracellular ATP concentrations.

  1. Sæbø PI, Bjørås M, Franzyk H, Helgensen E, Booth J (February 2, 2023). "Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity". Int. J. Mol. Sci. 24 (3). doi:10.3390/ijms24032914. PMC 9917735. PMID 36769243.