1-Androsterone - Misplaced Pages

(Redirected from 1-Dehydroepiandrosterone) Chemical compound Pharmaceutical compound

1-Androsterone
Clinical data

Other names	1-Andro; 1-Dehydroepiandrosterone; 1-DHEA; δ-Epiandrosterone; 1-Prasterone; 5α-Androst-1-en-3β-ol-17-one
Routes of administration	Oral
Identifiers
IUPAC name (3R,5S,8R,9S,10R,13S,14S)-3-Hydroxy-10,13-dimethyl-3,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopentaphenanthren-17-one
CAS Number	23633-63-8
PubChem CID	67430008
ChemSpider	48063738
UNII	U5M72D8OWZ
CompTox Dashboard (EPA)	DTXSID20737265
Chemical and physical data
Formula	C₁₉H₂₈O₂
Molar mass	288.431 g·mol
3D model (JSmol)	Interactive image
SMILES C12CC3(1CCC2=O)CC43(C=C(C4)O)C
InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,12-16,20H,3-6,8,10-11H2,1-2H3/t12-,13-,14-,15-,16-,18-,19-/m0/s1 Key:DYMROBVXGSLPAY-LUJOEAJASA-N

1-Androsterone (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) is a synthetic, orally active anabolic-androgenic steroid (AAS). It is an androgen prohormone of 1-testosterone (dihydroboldenone), 1-androstenedione, and other 1-dehydrogenated androstanes. The drug has been sold on the Internet as a designer steroid and "dietary supplement". It is a positional isomer of dehydroepiandrosterone (DHEA; 5-dehydroepiandrosterone).

References

^ Parr MK, Opfermann G, Geyer H, Westphal F, Sönnichsen FD, Zapp J, Kwiatkowska D, Schänzer W (2011). "Seized designer supplement named "1-Androsterone": identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination". Steroids. 76 (6): 540–7. doi:10.1016/j.steroids.2011.02.001. PMID 21310167. S2CID 4942690.

ARTooltip Androgen receptor

Agonists

17α-Alkylated 5α-dihydro-19-nortestosterone derivatives: 5α-Dihydronorethandrolone
5α-Dihydronormethandrone

5α-Dihydro-17α-ethynyl-19-nortestosterone derivatives: 5α-Dihydrolevonorgestrel
5α-Dihydronorethisterone

SARMsTooltip Selective androgen receptor modulator

Antagonists

Agonists	Cations (incl. aluminium, calcium, gadolinium, magnesium, strontium, zinc) Dehydroandrosterone Dihydrotestosterone Estradiol L-α-Amino acids (incl. L-arginine, L-lysine, L-ornithine) Osteocalcin SHBGTooltip Sex hormone-binding globulin Testosterone

See also: Receptor/signaling modulators; Androgens and antiandrogens; Estrogen receptor modulators; Progesterone receptor modulators; List of androgens and anabolic steroids

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