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1-hydroxy-2-naphthoate hydroxylase (EC 1.14.13.135, 1-hydroxy-2-naphthoic acid hydroxylase) is an enzyme with systematic name 1-hydroxy-2-naphthoate,NAD(P)H:oxygen oxidoreductase (2-hydroxylating, decarboxylating). This enzyme catalyses the following chemical reaction

1-hydroxy-2-naphthoate + NAD(P)H + H + O₂ ${\displaystyle \rightleftharpoons }$ 1,2-dihydroxynaphthalene + NAD(P)+ + H₂O + CO₂

1-hydroxy-2-naphthoate hydroxylase is involved in chrysene degradation in some bacteria.

References

1. Deveryshetty J, Phale PS (October 2010). "Biodegradation of phenanthrene by Alcaligenes sp. strain PPH: partial purification and characterization of 1-hydroxy-2-naphthoic acid hydroxylase". FEMS Microbiology Letters. 311 (1): 93–101. doi:10.1111/j.1574-6968.2010.02079.x. PMID 20727010.
2. Nayak AS, Sanjeev Kumar S, Santosh Kumar M, Anjaneya O, Karegoudar TB (July 2011). "A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04". FEMS Microbiology Letters. 320 (2): 128–34. doi:10.1111/j.1574-6968.2011.02301.x. PMID 21545490.

External links

• 1-hydroxy-2-naphthoate+hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 1.14.13