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The 1943 NCAA basketball tournament involved eight schools playing in single-elimination play to determine the national champion of men's NCAADivision Icollege basketball. It began on March 24, 1943, and ended with the championship game on March 30 in New York City. A total of nine games were played, including a third place game in each region. Top-ranked Illinois declined to participate in the NCAA tournament or NIT after three of its starters were drafted into the Army.
Wyoming, coached by Everett Shelton, won the national title with a 46–34 victory in the final game over Georgetown, coached by Elmer Ripley. Ken Sailors of Wyoming was named the tournament's Most Outstanding Player. The Cowboys were the first team in the 5-year history of the tournament to win after making a previous appearance in the tournament, having appeared in the 1941 tournament.