1st Guards Brigade may refer to:
German
- 1st Guards Cavalry Brigade (German Empire)
- 1st Guards Artillery Brigade (German Empire)
- 1st Guards Infantry Brigade (German Empire)
Others
- 1st Guards Brigade (Croatia)
- 1st Guards Infantry Brigade (Imperial Japanese Army)
- 1st Guards Armoured Brigade (Ukraine)
- 1st (Guards) Brigade designation for the British 1st Infantry Brigade at the outbreak of World War I and World War II
- 1st Guards Brigade (United Kingdom)
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