Names | |
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Preferred IUPAC name (2,4-Dichlorophenyl)methanol | |
Other names
Dybenal Rapidosept Myacide SP | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.015.646 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
InChI
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SMILES
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Properties | |
Chemical formula | C7H6Cl2O |
Molar mass | 177.02 g·mol |
Melting point | 57 to 60 °C (135 to 140 °F; 330 to 333 K) |
Boiling point | 150 °C (302 °F; 423 K) 25 mmHg |
Pharmacology | |
ATC code | R02AA03 (WHO) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references |
2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Cofsils, Strepsils, Lorsept, and Gorpils. It is also an ingredient in the European product Neo Borocillina. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (0.6 mg) has been found to deactivate respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus. A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5 to 10 minutes after brushing.
References
- "Neo Borocillina". drugs.com. Archived from the original on 2020-09-13. Retrieved 2018-01-23.
- Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral Chemistry & Chemotherapy. 16 (2): 129–34. doi:10.1177/095632020501600205. PMID 15889535.
- Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.
Throat preparations (R02) | |
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Antiseptics | |
Antibiotics | |
Local anesthetics | |
Other |