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2-Phosphoglyceric acid

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2-Phosphoglyceric acid
Names
IUPAC name 3-hydroxy-2-phosphonooxypropanoic acid
Other names 2PG
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)Key: GXIURPTVHJPJLF-UHFFFAOYSA-N
  • InChI=1/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)Key: GXIURPTVHJPJLF-UHFFFAOYAQ
SMILES
  • C(C(C(=O)O)OP(=O)(O)O)O
  • O=P(O)(O)OC(C(=O)O)CO
Properties
Chemical formula C3H7O7P
Molar mass 186.06 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

2-Phosphoglyceric acid (2PG), or 2-phosphoglycerate, is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.

In glycolysis

3-phospho-D-glycerate Phosphoglyceromutase 2-phospho-D-glycerate Enolase phosphoenolpyruvate
   
H2O
H2O
   
  Phosphoglyceromutase   Enolase

Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database. Enzyme 4.2.1.11 at KEGG Pathway Database. Compound C00074 at KEGG Pathway Database.

Click on genes, proteins and metabolites below to link to respective articles.

[[File:
GlycolysisGluconeogenesis_WP534go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to WikiPathwaysgo to articlego to Entrezgo to article
] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ] ]
GlycolysisGluconeogenesis_WP534go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to WikiPathwaysgo to articlego to Entrezgo to article
|alt=Glycolysis and Gluconeogenesis edit]] Glycolysis and Gluconeogenesis edit
  1. The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

See also

References

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Glycolysis metabolic pathway

Glucose

Hexokinase

ATP ADP Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right

Glucose 6-phosphate

Glucose-6-phosphate
isomerase

Reversible left-right reaction arrow

Fructose 6-phosphate

Phosphofructokinase-1

ATP ADP Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right

Fructose 1,6-bisphosphate

Fructose-bisphosphate
aldolase

Reversible left-right reaction arrow

Dihydroxyacetone phosphate

+

+

Glyceraldehyde 3-phosphate

Triosephosphate
isomerase

Reversible left-right reaction arrow

2 × Glyceraldehyde 3-phosphate

2 × 

Glyceraldehyde-3-phosphate
dehydrogenase

NAD+ Pi NADH + H Reversible left-right reaction arrow with minor forward substrate(s) from top left, minor forward product(s) to top right, minor reverse substrate(s) from bottom right and minor reverse product(s) to bottom leftNAD+ Pi NADH + H

2 × 1,3-Bisphosphoglycerate

2 × 

Phosphoglycerate kinase

ADP ATP Reversible left-right reaction arrow with minor forward substrate(s) from top left, minor forward product(s) to top right, minor reverse substrate(s) from bottom right and minor reverse product(s) to bottom leftADP ATP

2 × 3-Phosphoglycerate

2 × 

Phosphoglycerate mutase

Reversible left-right reaction arrow

2 × 2-Phosphoglycerate

2 × 

Phosphopyruvate
hydratase
(enolase)

  H2O Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right  H2O

2 × Phosphoenolpyruvate

2 × 

Pyruvate kinase

ADP ATP Rightward reaction arrow with minor substrate(s) from top left and minor product(s) to top right

2 × Pyruvate

2 × 
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