| Doubles | ||||
|---|---|---|---|---|
| 2010 Fifth Third Bank Tennis Championships | ||||
| Final | ||||
| Champions |  Raven Klaasen Izak van der Merwe | |||
| Runners-up |  Kaden Hensel Adam Hubble | |||
| Score | 5–7, 6–4, | |||
| Events | ||||
| ||||
| ||||
Kevin Anderson and Ryler DeHeart are the defending champions, but both chose not to participate.
Raven Klaasen and Izak van der Merwe won in the final against Kaden Hensel and Adam Hubble 5–7, 6–4, .
Seeds
Treat Conrad Huey / 
Dominic Inglot (semifinals)- Kaden Hensel / Adam Hubble (final)
Frederik Nielsen / Joseph Sirianni (quarterfinals)
Pierre-Ludovic Duclos / 
Nicholas Monroe (first round)
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Draw
| First round | Quarterfinals | Semifinals | Finals | ||||||||||||||||||||||||
| 1 | TC Huey D Inglot
| 6 | 6 | ||||||||||||||||||||||||
| Cory Parr V Pospisil
| 3 | 4 | 1 | TC Huey D Inglot
| 6 | 6 | |||||||||||||||||||||
| WC | S Bangoura D Kudla
| 6 | 4 | WC | S Bangoura D Kudla
| 2 | 2 | ||||||||||||||||||||
 R Hocevar J Souza
| 1 | 6 | 1 | TC Huey D Inglot
| 5 | 6 | |||||||||||||||||||||
| 3 | F Nielsen J Sirianni
| 4 | 6 | R Klaasen I van der Merwe
| 7 | 4 | |||||||||||||||||||||
 P Capdeville Z Zhang
| 6 | 4 | 3 | F Nielsen J Sirianni
| 3 | 5 | |||||||||||||||||||||
| M-X Gong Z Li
| 4 | 4 | R Klaasen I van der Merwe
| 6 | 7 | ||||||||||||||||||||||
| R Klaasen I van der Merwe
| 6 | 6 | R Klaasen I van der Merwe
| 5 | 6 | ||||||||||||||||||||||
| P Polansky M Raonic
| 6 | 6 | 2 | K Hensel A Hubble
| 7 | 4 | |||||||||||||||||||||
| WC | Phillip Arndt J Morrison
| 4 | 0 | P Polansky M Raonic
| w/o | ||||||||||||||||||||||
| A Bogomolov Jr. A Kuznetsov
| 0 | 6 | A Bogomolov Jr. A Kuznetsov
| ||||||||||||||||||||||||
| 4 | P-L Duclos N Monroe
| 6 | 4 | A Bogomolov Jr. A Kuznetsov
| 4 | 7 | |||||||||||||||||||||
 H Kondo T Suzuki
| 2 | K Hensel A Hubble
| 6 | 6 | |||||||||||||||||||||||
 R Berankis J Levine
| w/o | H Kondo T Suzuki
| 3 | 6 | |||||||||||||||||||||||
| WC | Jarmere Jenkins A Krajicek
| 6 | 3 | 2 | K Hensel A Hubble
| 6 | 3 | ||||||||||||||||||||
| 2 | K Hensel A Hubble
| 7 | 6 | ||||||||||||||||||||||||