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21U-RNAs are microRNA molecules 21 nucleotides long found in nematodes such as Caenorhabditis elegans. They begin with a 5' uridine. The remaining 20 nucleotides are diverse. They are modified at their 3′-terminal ribose. See Piwi-interacting RNA.
References
- Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP (December 2006). "Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans". Cell. 127 (6): 1193–1207. doi:10.1016/j.cell.2006.10.040. PMID 17174894. S2CID 16838469.