Two in One or 2-in-1 or variant may refer to:
- Two in One (film), a 2007 Russian film
- "Two in One", a 2016 song by Sonja Vectomov
- Marvel Two-in-One, an American comic book series
- Canon: Two in One, a musical term
- 2-in-1 PC, a cross between a tablet computer and a laptop
- Multi-function printer, a 2-in-1 printer, the 2-function versions which combines a printer with some other device, typically a scanner
- Two-in-one (juggling)
See also
- One in Two – Two in One (1979 album), album by Max Roach
- 2 of One (1989 album), a video album by Metallica
- Two to One (1978 album), album by Thelma Houston
- Two Is One (1974 album), album by Charles Rouse
- Two Is One, 2003 album by Andromeda
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