Misplaced Pages

3-hydroxybenzoate 2-monooxygenase

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Class of enzymes
3-hydroxybenzoate 2-monooxygenase
Identifiers
EC no.1.14.99.23
CAS no.73507-96-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 3-hydroxybenzoate 2-monooxygenase (EC 1.14.99.23) is an enzyme that catalyzes the chemical reaction

3-hydroxybenzoate + AH2 + O2 {\displaystyle \rightleftharpoons } 2,3-dihydroxybenzoate + A + H2O

The 3 substrates of this enzyme are 3-hydroxybenzoate, an electron acceptor AH2, and O2, whereas its 3 products are 2,3-dihydroxybenzoate, the reduction product A, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include 3-hydroxybenzoate 2-hydroxylase, and 3-HBA-2-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation.

References

Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14)
1.14.11: 2-oxoglutarate
1.14.13: NADH or NADPH
1.14.14: reduced flavin or flavoprotein
1.14.15: reduced iron–sulfur protein
1.14.16: reduced pteridine (BH4 dependent)
1.14.17: reduced ascorbate
1.14.18-19: other
1.14.99 - miscellaneous
Enzymes
Activity
Regulation
Classification
Kinetics
Types
Portal:


This EC 1.14 enzyme-related article is a stub. You can help Misplaced Pages by expanding it.

Categories: