The enzyme 3-phytase (EC 3.1.3.8) catalyzes the reaction
- myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate
myo-Inositol hexakisphosphate is also known as phytic acid.
These enzymes belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name myo-inositol-hexakisphosphate 3-phosphohydrolase. Other names in common use include 1-phytase, phytate 1-phosphatase, phytate 3-phosphatase, and phytate 6-phosphatase.
Enzymes of this type participate in inositol phosphate metabolism.
Structural studies
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes 1CVM, 1IHP, 1POO, 1QFX, 1QLG, 1QWO, 1SK8, 1SK9, 1SKA, 1SKB, 2GFI, and 2POO.
See also
- 4-phytase (6-phytase)
- 5-phytase
- Protein tyrosine phosphatase
References
- ^ "ENZYME entry 3.1.3.8". enzyme.expasy.org. Retrieved 2018-04-09.
- Mullaney EJ, Ullah AH (December 2003). "The term phytase comprises several different classes of enzymes". Biochemical and Biophysical Research Communications. 312 (1): 179–84. doi:10.1016/j.bbrc.2003.09.176. PMID 14630039.
| Hydrolase: esterases (EC 3.1) | |||||||||||||||
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| 3.1.1: Carboxylic ester hydrolases | |||||||||||||||
| 3.1.2: Thioesterase | |||||||||||||||
| 3.1.3: Phosphatase |
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| 3.1.4: Phosphodiesterase | |||||||||||||||
| 3.1.6: Sulfatase | |||||||||||||||
| Nuclease (includes deoxyribonuclease and ribonuclease) |
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