Names | |
---|---|
Other names 4-nitro-1,1′-biphenyl | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.002.005 |
EC Number |
|
KEGG | |
PubChem CID | |
RTECS number |
|
UNII | |
UN number | 2811 |
CompTox Dashboard (EPA) | |
InChI
| |
SMILES
| |
Properties | |
Chemical formula | C12H9NO2 |
Molar mass | 199.209 g·mol |
Melting point | 114 °C (237 °F; 387 K) |
Boiling point | 340 °C (644 °F; 613 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references |
4-Nitrobiphenyl is an organic compound with the formula C6H5−C6H4NO2. It is one of three isomers of nitrobiphenyl and probably the most widely used. It is a precursor to the antioxidant 4-aminobiphenyl. 4-Nitrobiphenyl is readily prepared by nitration of biphenyl. It can also be prepared by cross-coupling reactions.
4-Nitrobiphenyl is commonly invoked as a pollutant.
References
- Smith, Keith; Musson, Adam; Deboos, Gareth A. (1998). "A Novel Method for the Nitration of Simple Aromatic Compounds". The Journal of Organic Chemistry. 63 (23): 8448–8454. doi:10.1021/jo981557o.
- Wolfe, John P.; Singer, Robert A.; Yang, Bryant H.; Buchwald, Stephen L. (1999). "Highly Active Palladium Catalysts for Suzuki Coupling Reactions". Journal of the American Chemical Society. 121 (41): 9550–9561. doi:10.1021/ja992130h.
- Kovacic, Peter; Somanathan, Ratnasamy (2014). "Nitroaromatic compounds: Environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism". Journal of Applied Toxicology. 34 (8): 810–824. doi:10.1002/jat.2980. PMID 24532466.
- Fu, Peter P. (1990). "Metabolism of Nitro-Polycyclic Aromatic Hydrocarbons". Drug Metabolism Reviews. 22 (2–3): 209–268. doi:10.3109/03602539009041085. PMID 2272288.