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4-Phenyl-4-(1-piperidinyl)cyclohexanol

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4-Phenyl-4-(1-piperidinyl)cyclohexanol
Names
Preferred IUPAC name 4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol
Other names 4-Phenyl-4-(1-piperidinyl)cyclohexanol
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2Key: KPRUAZBLIREHPD-UHFFFAOYSA-N
  • InChI=1/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2Key: KPRUAZBLIREHPD-UHFFFAOYAM
SMILES
  • OC1CCC(N2CCCCC2)(C3=CC=CC=C3)CC1
  • OC3CCC(c1ccccc1)(N2CCCCC2)CC3
Properties
Chemical formula C17H25NO
Molar mass 259.391 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

4-Phenyl-4-(1-piperidinyl)cyclohexanol, also known as PPC, is an organic chemical which is a metabolite of phencyclidine (PCP). It can be detected in the hair of PCP users.

PPC has been shown to cause increases in locomotor activity in lab mice.

See also

  • PCHP, another PCP metabolite

References

  1. Nabeshima, Toshitaka; Yamaguchi, Kazumasa; Fukaya, Hiroaki; Hiramatsu, Masayuki; Furukawa, Hiroshi; Kameyama, Tsutomu (1985). "Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography". Research Communications in Substances of Abuse. 6 (2): 65–78.
  2. Nakahara, Yuji; Takahashi, Kazunori; Sakamoto, Tomoaki; Tanaka, Akira; Hill, Virginia A.; Baumgartner, Werner A. (1997). "Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use". Journal of Analytical Toxicology. 21 (5): 356–362. doi:10.1093/jat/21.5.356. PMID 9288587.
  3. "Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice".
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