| 4-methylaminobutanoate oxidase (methylamine-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.3.21 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
4-methylaminobutanoate oxidase (methylamine-forming) (EC 1.5.3.21, mao (gene)) is an enzyme with systematic name 4-methylaminobutanoate methylamidohydrolase. This enzyme catalyses the following chemical reaction
- 4-methylaminobutanoate + O2 + H2O succinate semialdehyde + methylamine + H2O2
The enzyme participates in the nicotine degradation in soil bacterium Arthrobacter nicotinovorans.
References
- Chiribau CB, Sandu C, Fraaije M, Schiltz E, Brandsch R (December 2004). "A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1" (PDF). European Journal of Biochemistry. 271 (23–24): 4677–84. doi:10.1111/j.1432-1033.2004.04432.x. PMID 15606755.
- Chiribau CB, Mihasan M, Ganas P, Igloi GL, Artenie V, Brandsch R (April 2006). "Final steps in the catabolism of nicotine". The FEBS Journal. 273 (7): 1528–36. doi:10.1111/j.1742-4658.2006.05173.x. PMID 16689938.
External links
- 4-methylaminobutanoate+oxidase+(methylamine-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
| Oxidoreductases: CH-NH (EC 1.5) | |
|---|---|
| 1.5.1: NAD or NADP acceptor | |
| 1.5.3: oxygen acceptor | |
| 1.5.5: quinone acceptor | |
| 1.5.99 | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
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